MEDULLOBLASTOMA
Clinical trials for MEDULLOBLASTOMA explained in plain language.
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Brain cancer trial tests tailored therapy to reduce side effects
Disease control TerminatedThis trial tested a personalized treatment approach for post-pubertal patients with a rare brain cancer called medulloblastoma. It aimed to use a targeted drug (sonidegib) and lower radiation doses for patients with a specific genetic subtype (SHH-activated) to improve effectiven…
Matched conditions: MEDULLOBLASTOMA
Phase: PHASE2 • Sponsor: European Organisation for Research and Treatment of Cancer - EORTC • Aim: Disease control
Last updated May 15, 2026 11:54 UTC
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Promising brain tumor drug trial halted early – what we know
Disease control TerminatedThis study tested a drug called CX-4945 in children whose SHH medulloblastoma (a brain tumor) had come back. The goal was to find the best dose and see if it could shrink tumors. The trial was stopped early, but it involved 21 participants and looked at how the drug worked in the…
Matched conditions: MEDULLOBLASTOMA
Phase: PHASE1, PHASE2 • Sponsor: Pediatric Brain Tumor Consortium • Aim: Disease control
Last updated May 11, 2026 20:52 UTC
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Could a simple fluid test replace brain surgery for kids with tumors?
Knowledge-focused TerminatedThis study looked at whether a liquid biopsy—testing the fluid around the brain and spinal cord—can find tumor DNA in children and young adults with brain tumors. Researchers collected extra samples during routine care from up to 57 participants. The goal was to see if this safer…
Matched conditions: MEDULLOBLASTOMA
Sponsor: Pediatric Brain Tumor Consortium • Aim: Knowledge-focused
Last updated May 06, 2026 16:01 UTC