MEDULLOBLASTOMA
Clinical trials for MEDULLOBLASTOMA explained in plain language.
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Promising drug for recurrent brain tumor in kids falls short in early trial
Disease control TerminatedThis study tested an oral drug called CX-4945 (silmitasertib) in 21 children with recurrent SHH medulloblastoma, a rare brain tumor. The trial aimed to find the best dose and see if the drug could shrink tumors. However, the study was stopped early, so we don't have clear answers…
Matched conditions: MEDULLOBLASTOMA
Phase: PHASE1, PHASE2 • Sponsor: Pediatric Brain Tumor Consortium • Aim: Disease control
Last updated Jun 27, 2026 07:56 UTC
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Tailored therapy for medulloblastoma shows promise but trial cut short
Disease control TerminatedThis phase 2 trial tested a personalized treatment approach for post-pubertal patients with newly diagnosed medulloblastoma, a rare brain cancer. The experimental group received a targeted drug called sonidegib along with reduced radiation, based on the tumor's genetic subtype. T…
Matched conditions: MEDULLOBLASTOMA
Phase: PHASE2 • Sponsor: European Organisation for Research and Treatment of Cancer - EORTC • Aim: Disease control
Last updated Jun 27, 2026 07:55 UTC
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Spinal tap could replace brain surgery for young tumor patients
Knowledge-focused TerminatedThis study looked at whether a liquid biopsy—testing the fluid around the brain and spinal cord—can find tumor DNA in children and young adults with brain tumors. The goal was to see if this safer, non-surgical test could replace risky tissue biopsies for diagnosis and monitoring…
Matched conditions: MEDULLOBLASTOMA
Sponsor: Pediatric Brain Tumor Consortium • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC