MEDULLOBLASTOMA

This study tests a thyroid hormone called liothyronine (L-T3) alone or with standard chemotherapy in children and young adults whose medulloblastoma has come back or worsened. The goal is to see if adding L-T3 can help control the cancer better. About 69 participants will take pa…

This study looks at a new way to give radiation to children with brain tumors that need whole-brain and whole-spine treatment. The technique, called vertebral body-sparing proton therapy, aims to protect the front of the spine bones to preserve bone marrow and growth. Researchers…

This early-phase study tests the safety of a new cell therapy called B7-H3 CAR T cells for children and young adults whose brain tumors have come back or are growing despite standard treatment. The therapy uses the patient's own immune cells, modified to target a protein (B7-H3) …

This phase 3 trial compares two standard chemotherapy regimens for children under 5 with a low-risk type of medulloblastoma. The main goal is to see which approach better protects thinking and learning skills 2.5 years after diagnosis. The study will also track survival and side …

This study tests a lab technique called pharmacoscopy that analyzes a patient's tumor tissue to find which drugs might work best for them. It includes 40 adults with various aggressive or rare brain tumors that have not responded to standard treatments. The main goal is to see if…

This study is testing a mobile app called my.naviGATE for teens and young adults (ages 15-24) who have finished cancer treatment. The app provides personalized education, peer support, and tracks how patients are doing. Researchers want to see if the app helps patients feel more …