New hope for kids with brain cancer: experimental drug APX005M tested
NCT ID NCT03389802
First seen Nov 01, 2025 · Last updated Apr 30, 2026 · Updated 31 times
Summary
This early-phase study tested an experimental drug called APX005M in 32 children with brain tumors that had come back or were hard to treat, including a type of brain stem glioma. The goal was to find the safest dose and see if the drug could help the immune system attack the tumor. The study focused on side effects and did not aim to cure the disease.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Baylor College of Medicine
Houston, Texas, 77030, United States
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Children Hospital of Pittsburgh of UPMC
Pittsburgh, Pennsylvania, 15224, United States
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Children's Healthcare of Atlanta
Atlanta, Georgia, 30322, United States
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Children's Hospital Colorado
Aurora, Colorado, 80045, United States
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Children's Hospital Los Angeles
Los Angeles, California, 90026, United States
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Childrens National Medical Center
Washington D.C., District of Columbia, 20010-2970, United States
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Cincinnati Children Hospital Medical Center
Cincinnati, Ohio, 45229, United States
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Lucile Packard Children Hospital Stanford University
Palo Alto, California, 94304, United States
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Lurie Childrens Hospital-Chicago
Chicago, Illinois, 60614, United States
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Memorial Sloan Kettering Cancer Center
New York, New York, 10065, United States
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St. Jude Children Research Hospital
Memphis, Tennessee, 38105, United States
Conditions
Explore the condition pages connected to this study.