LUNG DISEASES

This study tested an experimental drug called vapendavir in 52 adults with COPD (a chronic lung disease). The goal was to see if the drug could reduce severe cold symptoms caused by rhinovirus, a common cold virus. Participants were given either vapendavir or a placebo and monito…

This study looked at whether taking vitamin D every day can lower the risk of serious lung problems in children and teens with sickle cell disease. Lung issues like infections and acute chest syndrome are major causes of illness in this group. The study involved 58 participants a…

This study tested an experimental pill called ralinepag for people with pulmonary arterial hypertension (PAH), a serious lung condition that makes the heart work too hard. About 687 adults with PAH took either ralinepag or a placebo on top of their usual treatments. The goal was …

This study looked at whether a simple checklist called the YEARS algorithm can safely rule out dangerous blood clots in the lungs (pulmonary embolism) in people with active cancer, without needing a CT scan. About 700 participants were randomly assigned to either the YEARS approa…

This study tested giving extra numbing medicine (lidocaine or alfentanil) through an IV just before inserting a bronchoscope (a tube to look at the lungs). The goal was to see if it could prevent severe coughing when the doctor sprays anesthetic inside the airway. 108 adults havi…

This study tested a nerve-freezing technique (cryoanalgesia) during robot-assisted lung surgery to see if it reduces pain afterward. 33 adults having lung surgery were randomly assigned to receive the nerve block or not. Researchers measured pain scores and pain medication use fo…

This study tested a new device called Neola® that monitors the lungs of newborn babies. Ten preterm or full-term infants were enrolled to see if the device is safe and works well. The main goal was to check for any side effects, like skin reactions, while the babies rested.

This study tested whether a new, thinner freezing probe (cryoprobe) works better than the usual forceps for taking lung tissue samples during a bronchoscopy. About 500 adults with lung disease took part. The main goal was to see which tool leads to a clear diagnosis more often, w…

This study looked at whether firefighters have different lung scan results compared to non-firefighters. Researchers used low-dose CT scans to check for lung nodules and other lung diseases in 734 current and retired firefighters. The goal was to better understand how job-related…

This study looked at whether a person's blood group antigens are connected to asthma attacks. Researchers followed 126 people with asthma to see if certain blood types had more flare-ups needing steroids. The goal was to understand, not to test a new treatment.

This study tested a new device called AirWaze that helps doctors guide a thin tube (bronchoscope) to the right spot in the lungs during a biopsy. 37 adults with lung lesions took part. The main goals were to see if the device was easy to use and if a special low-dose scan could c…

This study looked at whether a coordinated team approach to managing sedative drugs could help children with acute respiratory failure spend fewer days on a mechanical ventilator. Over 2,400 children from age 2 weeks to 18 years participated. The goal was to find a safer, more ef…

This early-phase study looked at carnitine, a nutrient found in food, in people with pulmonary arterial hypertension (PAH). Researchers wanted to see if carnitine levels are stable and if taking supplements could increase carnitine in the blood, potentially helping the heart. Ten…