Can a simple injection stop coughing during lung procedures?
NCT ID NCT05072236
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether giving lidocaine or alfentanil before inserting a bronchoscope can reduce coughing when spraying numbing medicine into the airways. 108 adults with lung tumors received one of these drugs or a placebo before the procedure. Researchers measured cough severity, brain activity, and vital signs to see which drug worked best.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
lidocaine and alfentanil
What this could lead to
If it works, this could point toward a simple way to reduce coughing during bronchoscopy, making the procedure safer and more comfortable.
What could go wrong
This is a small, completed study with 108 participants, so results may not apply to all patients. The drugs may not significantly reduce cough or could cause side effects like drowsiness or low blood pressure.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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National Taiwan University Cancer Center Hospital
Taipei, Taiwan