LUNG DISEASES

This program provides access to the experimental drug taletrectinib for adults with advanced ROS1-positive lung cancer who have run out of approved treatment options and cannot join regular clinical trials. The drug aims to control cancer growth in patients who have already tried…

This study continues testing ralinepag, an experimental medication for pulmonary arterial hypertension (PAH), to understand its long-term safety and effectiveness. It enrolls 1,000 participants who have already taken ralinepag in previous studies and are already on standard PAH m…

This study aimed to test a specialized catheter designed to deliver clot-dissolving medication directly to blood clots in the lungs. It planned to enroll up to 10 adults with serious but not massive lung clots. The trial was withdrawn by the sponsor before any patients were enrol…

This study is observing how well a combination of the drug Osimertinib and standard chemotherapy works for people with a specific type of advanced lung cancer (EGFR-positive NSCLC) in a real-world setting. It involves 532 adult patients who have already started this specific trea…

This study is testing a new medical device called the Aventus Thrombectomy System. It is designed to physically remove dangerous blood clots from the lungs of patients with a sudden, severe pulmonary embolism. The trial will enroll 130 adults to see if the procedure is safe and e…

This study is testing whether an inhaled drug called mosliciguat is safe and effective for people who have high blood pressure in their lungs (pulmonary hypertension) caused by underlying lung scarring (interstitial lung disease). About 135 participants will be randomly assigned …

This study is testing whether a combination of fish oil (Lovaza) and curcumin (from turmeric) can help reduce the size of small lung nodules found in former and current heavy smokers. The goal is to see if these natural supplements might help prevent lung problems before they bec…

This study aims to see if providing standardized training to cancer doctors in smaller city and county hospitals leads to better testing and treatment for patients with advanced non-small cell lung cancer. It will follow 1,000 patients to measure if doctors order more recommended…

This study aims to understand how diseases in the lungs, digestive system, or endocrine (hormone) glands affect brain activity over time. Researchers will use a special type of brain scan (PET/CT) on 200 participants to see if changes in brain energy use can predict future health…

This study aims to understand why lung disease varies so much in people with cystic fibrosis (CF), even when they have the same genetic mutation. Researchers are analyzing the DNA of 600 CF patients to identify other genes that might make the lung disease milder or more severe. T…

This study aims to collect lung sound recordings from 750 adults to train a computer algorithm. The goal is to develop an AI tool that can help doctors identify sounds linked to lung conditions. Participants include both healthy people and those with suspected or diagnosed lung i…