Curcumin and fish oil tested to shrink Smokers' lung nodules

NCT ID NCT03598309

Ongoing Disease control Sponsor: H. Lee Moffitt Cancer Center and Research Institute Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This phase 2 trial tests whether a combination of curcumin (from turmeric) and fish oil can reduce the size of lung nodules in former and current smokers aged 55 and older. Nineteen participants took the supplements or a placebo for 6 months. The study aims to see if the nodules shrink and if the treatment is safe.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Curcumin C3 Complex and Omega-3-Acid Ethyl Esters (fish oil)
What this could lead to: If it works, this could point toward a way to reduce lung nodules in smokers, potentially lowering cancer risk.
What could go wrong: This is a very small, early-phase trial with only 19 participants. The results may not apply to everyone, and the supplements might not shrink nodules or could cause side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

lung cancer lung disorder lung neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LUNG CANCER, PROTECTION AGAINST LUNG DISEASES

Contacts and locations

Locations

H. Lee Moffitt Cancer Center and Research Institute

Tampa, Florida, 33612, United States

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