LUNG CARCINOMA

This study tests a new drug called SKB518 in 192 people with lung cancer. The goal is to see if it is safe and can shrink tumors. Participants receive the drug alone until their disease gets worse or side effects become too strong.

This study tests whether artificial intelligence (AI) can help doctors choose the right radiation dose for lung tumors. About 70 people with lung cancer or tumors that spread to the lung will receive precise, high-dose radiation (SBRT) with doses guided by an AI tool. The goal is…

This study looks at whether finding and treating COPD early can help people who are also being evaluated for lung cancer. About 280 adults with breathing problems will get early COPD treatment or standard care. Researchers will track symptoms, weight, and exercise ability over 6 …

This study tests a special dye that attaches to lung cancer cells and makes them glow under a special camera during surgery. The goal is to help surgeons see and remove all cancer tissue more accurately. About 30 adults with lung cancer or lung metastases will receive the dye bef…

This study looks at whether a simple at-home blood test (liquid biopsy) can make lung cancer screening easier and more appealing for high-risk smokers and former smokers aged 50-80. Currently, only a few people get the recommended CT scan. The blood test looks for tiny bits of ca…

This study tests whether using community advocates can increase the number of people who get screened for breast and lung cancer. Researchers will enroll 800 eligible adults and track how many complete their recommended screenings. The goal is to understand psychological barriers…

This study tests whether the drug canakinumab can prevent lung cancer in 50 people who have suspicious lung nodules that haven't gone away. Participants receive the drug and are monitored for nodule shrinkage, cancer development, and side effects. The goal is to see if this appro…

This study tests whether telephone-based physical activity coaching can improve physical function in older adults (65+) undergoing lung cancer surgery, compared to self-monitored activity. Both patients and their family caregivers will participate. The goal is to see if remote co…

This study compares giving cancer treatment at home versus in a clinic for 27 adults with various cancers in the Florida Panhandle. The goal is to see if patients prefer home care and if it is safe. Participants will receive their usual cancer drugs either at home or in the clini…

This study looks at whether giving veterans with lung cancer extra support can help them feel better day-to-day. Researchers will track quality of life, emergency room visits, and hospital stays over one year. The goal is to find simple ways to improve care for those who served.

This study reviews medical records of 600 lung cancer patients who had surgery between 2004 and 2019. Researchers want to see if robotic surgery has led to more atypical segmentectomies (removing part of a lung lobe in an unusual way). The goal is to understand trends, not to tes…

This study looks at how walking and sleeping habits affect recovery after lung cancer surgery. Researchers will give some patients a Fitbit to track their steps and sleep. The goal is to learn if more walking leads to fewer complications and better quality of life after surgery.

This study looks at whether teaching doctors and patients about lung cancer screening can increase the number of people who get screened. It involves about 822 adults with a history of smoking. The goal is to find lung cancer earlier, when it's easier to treat.

This study tests whether a short screening tool can help people with advanced lung cancer better understand their illness and treatment options. Researchers will compare patients who use the tool with those who receive usual care. The goal is to see if the tool helps patients mak…

This study tests a program called CONNECTing to LungCare that helps smokers and their doctors have better conversations about quitting smoking and getting screened for lung cancer. The program gives patients information and a summary to share with their doctor. The study will see…

This study aims to see if low-dose CT scans are a good way to screen for lung cancer in Black individuals aged 50-80 who have smoked. Researchers will enroll 900 participants to check how many people agree to join and how well the scans find cancer. The goal is to improve early d…

This study tests whether a CPAP device (commonly used for sleep apnea) can reduce tumor movement during lung cancer radiation therapy. About 30 people will compare CPAP with the standard breath-holding technique. The goal is to see which method better stabilizes the tumor, potent…

This study gathers information on short- and long-term side effects from proton therapy in adults with various cancers. Researchers will collect data from up to 5,000 participants to better understand and predict these side effects. The goal is to improve future treatment plannin…

This study tests an online platform for people with lung, colorectal, breast, or prostate cancer to track medication side effects and concerns at home. About 80 participants will use the tool and report on its ease of use and how it affects their health. The goal is to see if sel…

This study uses special PET/CT scans to see how radiation therapy for lung or esophageal cancer affects the heart. About 20 adults getting radiation will have heart scans before, during, and after treatment. The goal is to learn if these scans can detect heart changes caused by r…

This study at Mayo Clinic is testing whether robotic biopsies can collect enough lung tumor tissue to analyze its genes. The goal is to learn more about hereditary and cancer-related genetic changes, and to build a databank for future research. About 40 adults at risk for lung ca…

This study is testing whether a new radioactive imaging agent can safely and clearly show tumors in people with many types of solid cancers. About 32 adults will receive a single injection of the agent and then have PET/CT scans to see where it goes in the body. The goal is to le…

This study looks at the best ways to teach heavy smokers about lung cancer screening using tobacco quitlines. Researchers will work with 800 people, including quitline staff and smokers aged 55-80 with a heavy smoking history. The goal is to see how well these methods help smoker…

This study is testing new blood tests that look for signs of many different cancers at the same time. Researchers want to see if these tests can find cancer early, when treatment works best. About 24,000 adults aged 45 to 75 who do not have cancer will be split into three groups:…