Could a simple home blood test spot lung cancer earlier?

NCT ID NCT05384769

Recruiting now Diagnosis Sponsor: City of Hope Medical Center Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether a cell-free DNA liquid biopsy done at home can help screen for lung cancer in high-risk current and former smokers aged 50-80. Participants will either use the liquid biopsy or get a standard low-dose CT scan. The goal is to see if the home test encourages more people to get screened and catch lung cancer earlier.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Cell-free DNA liquid biopsy
What this could lead to: If successful, this could make lung cancer screening easier and more accessible, catching the disease earlier in people at high risk.
What could go wrong: This is a small feasibility study, not a large trial. The liquid biopsy may miss some cancers or give false alarms, and it's not yet proven to be better than standard CT screening.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

lung carcinoma lung neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LUNG CARCINOMA

Contacts and locations

Locations

City of Hope Medical Center
RECRUITING

Duarte, California, 91010, United States

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