New blood test could spot 10 cancers before symptoms start

NCT ID NCT06995898

First seen Jun 27, 2026 · Last updated Aug 14, 2026 · Updated 6 times

Summary

This study is testing whether a new blood test can screen for many types of cancer at once. Researchers will enroll 24,000 adults aged 45-75 who do not have cancer. Participants will be randomly assigned to one of two blood test groups or a control group. The goal is to see how well these tests work and how people and their doctors respond to the results.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Multi-Cancer Detection (MCD) blood test
What this could lead to
If successful, this could lead to a simple blood test that finds many types of cancer early, when treatment works best.
What could go wrong
This is an early feasibility study, not a final test. The blood tests may not be accurate enough, and results may not apply to everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Cancer Care and Hematology-Fort Collins

    RECRUITING

    Fort Collins, Colorado, 80528, United States

  • Henry Ford Cancer Institute-Downriver

    RECRUITING

    Brownstown, Michigan, 48183, United States

    Contact Email: •••••@•••••

  • Henry Ford Health Center - Brownstown

    RECRUITING

    Brownstown, Michigan, 48183, United States

  • Henry Ford Health Center - Chesterfield

    RECRUITING

    Chesterfield, Michigan, 48047, United States

  • Henry Ford Hospital

    RECRUITING

    Detroit, Michigan, 48202, United States

    Contact Email: •••••@•••••

  • Henry Ford Macomb Hospital-Clinton Township

    RECRUITING

    Clinton Township, Michigan, 48038, United States

    Contact Email: •••••@•••••

  • Henry Ford Medical Center

    RECRUITING

    Sterling Heights, Michigan, 48310, United States

  • Henry Ford Medical Center - Detroit Northwest

    RECRUITING

    Detroit, Michigan, 48235, United States

  • Henry Ford Medical Center - Livonia

    RECRUITING

    Livonia, Michigan, 48150, United States

  • Henry Ford Medical Center - Plymouth

    RECRUITING

    Plymouth, Michigan, 48170, United States

  • Henry Ford Medical Center - Royal Oak

    RECRUITING

    Royal Oak, Michigan, 48067, United States

  • Henry Ford Medical Center - Troy

    RECRUITING

    Troy, Michigan, 48083, United States

  • Henry Ford Medical Center-Columbus

    RECRUITING

    Novi, Michigan, 48377, United States

    Contact Email: •••••@•••••

  • Henry Ford Medical Center-Cottage

    RECRUITING

    Grosse Pointe Farms, Michigan, 48236, United States

  • Henry Ford Medical Center-Fairlane

    RECRUITING

    Dearborn, Michigan, 48126, United States

    Contact Email: •••••@•••••

  • Henry Ford West Bloomfield Hospital

    RECRUITING

    West Bloomfield, Michigan, 48322, United States

    Contact Email: •••••@•••••

  • Henry Ford Wyandotte Hospital

    RECRUITING

    Wyandotte, Michigan, 48192, United States

  • Inova Fair Oaks Hospital

    RECRUITING

    Fairfax, Virginia, 22033, United States

  • Inova Schar Cancer Institute

    RECRUITING

    Fairfax, Virginia, 22031, United States

  • Kaiser Permanente Moanalua Medical Center

    RECRUITING

    Honolulu, Hawaii, 96819, United States

  • Kaiser Permanente-Division of Research

    RECRUITING

    Pleasanton, California, 94588, United States

  • Kaiser Permanente-Franklin

    RECRUITING

    Denver, Colorado, 80205, United States

    Contact Email: •••••@•••••

  • Kaiser Permanente-Lone Tree

    RECRUITING

    Lone Tree, Colorado, 80124, United States

    Contact Email: •••••@•••••

  • Kaiser Permanente-Rock Creek

    RECRUITING

    Lafayette, Colorado, 80026, United States

    Contact Email: •••••@•••••

  • Keefe Memorial Hospital

    RECRUITING

    Cheyenne Wells, Colorado, 80810, United States

  • Madigan Army Medical Center

    RECRUITING

    Tacoma, Washington, 98431, United States

  • Medical Center of the Rockies

    RECRUITING

    Loveland, Colorado, 80538, United States

  • Minneapolis VA Medical Center

    RECRUITING

    Minneapolis, Minnesota, 55417, United States

  • Poudre Valley Hospital

    RECRUITING

    Fort Collins, Colorado, 80524, United States

  • Saint Luke's Hospital of Kansas City

    RECRUITING

    Kansas City, Missouri, 64111, United States

  • Sentara Martha Jefferson Hospital

    RECRUITING

    Charlottesville, Virginia, 22911, United States

  • Sentara Norfolk General Hospital

    RECRUITING

    Norfolk, Virginia, 23507, United States

  • UCHealth Greeley Hospital

    RECRUITING

    Greeley, Colorado, 80631, United States

  • UNC Lineberger Comprehensive Cancer Center

    RECRUITING

    Chapel Hill, North Carolina, 27599, United States

    Contact Email: •••••@•••••

  • University of Oklahoma Health Sciences Center

    RECRUITING

    Oklahoma City, Oklahoma, 73104, United States

  • VCU Community Memorial Health Center

    RECRUITING

    South Hill, Virginia, 23970, United States

  • VCU Massey Cancer Center at Stony Point

    RECRUITING

    Richmond, Virginia, 23235, United States

  • VCU Massey Comprehensive Cancer Center

    RECRUITING

    Richmond, Virginia, 23298, United States

  • Walter Reed National Military Medical Center

    RECRUITING

    Bethesda, Maryland, 20889-5600, United States

  • Washington University School of Medicine

    RECRUITING

    St Louis, Missouri, 63110, United States

    Contact Email: •••••@•••••

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