LONELINESS
Clinical trials for LONELINESS explained in plain language.
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Loneliness therapy may curb opioid misuse in pain patients
Disease control CompletedThis completed study tested whether reducing loneliness through group therapy could lower opioid misuse in 102 adults on long-term opioids for chronic pain. Participants received either cognitive behavior therapy or social navigation in weekly sessions. Researchers measured chang…
Matched conditions: LONELINESS
Phase: NA • Sponsor: University of Washington • Aim: Disease control
Last updated Jun 27, 2026 08:10 UTC
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Loneliness fix? music, exercise, and education show promise in small trial
Symptom relief CompletedThis completed study tested a combination of music therapy, health education, and physical exercise in 20 older adults (over 60) living in Valencia who felt unwanted loneliness. The goal was to see if these group activities could reduce loneliness and improve mental health. Becau…
Matched conditions: LONELINESS
Phase: NA • Sponsor: University of Valencia • Aim: Symptom relief
Last updated Jun 27, 2026 13:07 UTC
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Music therapy shows promise for stressed teens
Symptom relief CompletedThis study tested a 4-week music program called 'Tuned In' for 133 Hong Kong teens struggling with low mood, anxiety, or loneliness. Participants were randomly assigned to start the program right away or wait 4 weeks. The program, led by a psychologist and music therapist, aimed …
Matched conditions: LONELINESS
Phase: NA • Sponsor: The University of Hong Kong • Aim: Symptom relief
Last updated Jun 27, 2026 13:03 UTC
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Phone-Based program aims to boost mood and mobility in seniors
Symptom relief CompletedThis study tested a program called RESET, led by community health workers, to improve physical and mental well-being in older adults. Over 450 African American adults aged 50+ with symptoms like depression, anxiety, or chronic pain took part. The program included weekly group pho…
Matched conditions: LONELINESS
Phase: NA • Sponsor: University of Michigan • Aim: Symptom relief
Last updated Jun 27, 2026 13:00 UTC
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Magnetic pulses may reignite motivation in memory-loss veterans
Symptom relief CompletedThis study tested whether transcranial magnetic stimulation (TMS) can reduce apathy—a severe lack of motivation—in older veterans with mild cognitive impairment (MCI). About 103 participants received either real or fake TMS over 20 sessions. The goal was to see if TMS could impro…
Matched conditions: LONELINESS
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Symptom relief
Last updated Jun 27, 2026 12:36 UTC
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Robot buddy tested to combat loneliness in seniors
Symptom relief CompletedThis study tested whether a humanoid robot named HUMANE could help older adults living at home feel less lonely and more connected. Sixty people aged 50 and older used the robot for 6 weeks, interacting with it through music, news, games, and conversation. Researchers measured lo…
Matched conditions: LONELINESS
Phase: NA • Sponsor: The Hong Kong Polytechnic University • Aim: Symptom relief
Last updated Jun 27, 2026 12:36 UTC
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Virtual hugs: AR headsets battle senior loneliness
Symptom relief CompletedThis study tested whether using augmented reality (AR) headsets could help older adults feel less lonely. Sixteen older adults and their family members used AR to do activities together over 4 weeks. Researchers measured how easy and enjoyable the technology was to use, and wheth…
Matched conditions: LONELINESS
Phase: NA • Sponsor: Vanderbilt University • Aim: Symptom relief
Last updated Jun 27, 2026 12:29 UTC
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Can a weekly chat with fellow veterans lift depression? small study says maybe.
Symptom relief CompletedThis completed study tested whether weekly peer-led social groups could help older veterans struggling with depression and loneliness. Eighteen veterans took part in 16 weeks of group meetings. Researchers measured changes in mood, social support, and loneliness using questionnai…
Matched conditions: LONELINESS
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Symptom relief
Last updated Jun 27, 2026 12:25 UTC
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New online program aims to ease loneliness for dementia caregivers
Symptom relief CompletedThis study tested a web-based program called RELOAD-C designed to reduce loneliness in people caring for a family member or friend with Alzheimer's disease. The program uses short videos and online group discussions based on Meaning-Centered Psychotherapy to help caregivers find …
Matched conditions: LONELINESS
Phase: NA • Sponsor: Northwell Health • Aim: Symptom relief
Last updated Jun 27, 2026 12:04 UTC
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Prayer app boosts student mental health in new study
Symptom relief CompletedThis study tested a faith-based mobile app called PRAY.COM to see if it helps university students feel better mentally and emotionally. About 450 students used the app for at least 10 minutes each day over 8 weeks. Researchers checked if students liked the app and used it regular…
Matched conditions: LONELINESS
Phase: NA • Sponsor: Fit Minded • Aim: Symptom relief
Last updated Jun 27, 2026 12:00 UTC
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Gardening therapy blooms hope for lonely seniors in nursing homes
Symptom relief CompletedThis study looked at whether gardening activities (horticultural therapy) can reduce loneliness and improve life satisfaction in older adults living in nursing homes. 54 people aged 60 and older took part. The therapy involved hands-on gardening to encourage social interaction an…
Matched conditions: LONELINESS
Phase: NA • Sponsor: Istanbul University - Cerrahpasa • Aim: Symptom relief
Last updated Jun 27, 2026 09:05 UTC
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Can social connection prevent suicide? new study targets lonely latino adults
Symptom relief CompletedThis study tested a program called Social Engage (S-ENGAGE) designed to help Spanish-speaking Latino adults who feel socially isolated and have suicidal thoughts. The program uses action planning to help participants set goals and take steps to increase their cultural-social acti…
Matched conditions: LONELINESS
Phase: NA • Sponsor: University of Rochester • Aim: Symptom relief
Last updated Jun 27, 2026 09:00 UTC
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Volunteer phone calls may ease loneliness in seniors
Symptom relief CompletedThis study tested whether trained volunteers (retirees and young people) could help reduce loneliness in adults aged 65+ by delivering mindfulness or behavioral activation exercises over the phone. 251 older adults in Hong Kong took part. The goal was to see if these simple, low-…
Matched conditions: LONELINESS
Phase: NA • Sponsor: Education University of Hong Kong • Aim: Symptom relief
Last updated Jun 27, 2026 08:05 UTC
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Coaching program aims to combat loneliness and suicide in seniors
Symptom relief CompletedThis study tested a coaching program called Social Engage Coaching for adults aged 60 and older who feel lonely and have had thoughts of suicide. The program involves up to 10 one-on-one sessions with a trained coach to help build social connections. Researchers measured loneline…
Matched conditions: LONELINESS
Phase: NA • Sponsor: University of Rochester • Aim: Symptom relief
Last updated Jun 27, 2026 08:05 UTC
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Friendly phone calls may ease loneliness and suicide risk in seniors
Symptom relief CompletedThis completed study tested whether regular, friendly phone calls from trained volunteers could improve mental health in older adults at risk of loneliness and suicide. Over 670 participants aged 55+ received weekly calls for 8 weeks. Researchers measured changes in loneliness, d…
Matched conditions: LONELINESS
Phase: NA • Sponsor: University of Florida • Aim: Symptom relief
Last updated Jun 27, 2026 07:57 UTC
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New coaching program aims to ease loneliness for latino dementia caregivers
Symptom relief CompletedThis study tested a brief psychotherapy called Social Engage for Hispanic/Latino caregivers aged 40 and older who care for a family member with dementia and feel lonely or stressed. Ten participants received up to 8 weekly sessions by phone or video over 3 months. The goal was to…
Matched conditions: LONELINESS
Phase: NA • Sponsor: University of Rochester • Aim: Symptom relief
Last updated Jun 27, 2026 07:55 UTC
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Your friendships may predict your mental health: stanford study follows 10,000 students
Knowledge-focused CompletedThis study followed nearly 10,000 Stanford undergraduates over their college years to understand how social ties, loneliness, and stress relate to anxiety and depression. Researchers used surveys and social network analysis to track changes in mental health. The goal is to create…
Matched conditions: LONELINESS
Phase: NA • Sponsor: Stanford University • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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Screen time secrets: new study reveals how Kids' devices impact mood and sleep
Knowledge-focused CompletedThis study looked at how children ages 8 to 17 use smartphones and tablets, including social media and games, and how that relates to their mental health, sleep, and physical activity. Over 900 children and their parents used the Aura app and completed surveys for three months. T…
Matched conditions: LONELINESS
Sponsor: Aura • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:08 UTC
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Postcards from peers: a new weapon against veteran loneliness?
Knowledge-focused CompletedThis study looked at whether sending caring postcards from fellow Veterans can reduce loneliness and improve mental health in older Veterans. Nearly 1,000 Veterans aged 50 and older who had missed VA appointments took part. They received up to 10 postcards and completed surveys t…
Matched conditions: LONELINESS
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:03 UTC
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Video games and veggies: new program aims to boost teen Well-Being
Knowledge-focused CompletedThis study tested a 25-week program called eHOOD for teens with challenges like anxiety, loneliness, or ADHD. Each week, participants did physical activities, cooked and ate dinner together, learned about healthy habits, and played online games as a group. The goal was to see if …
Matched conditions: LONELINESS
Phase: NA • Sponsor: Center for Clinical Research and Prevention • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Chilean pain study reveals hidden toll on mental health
Knowledge-focused CompletedThis study followed 2,365 adults from urban areas of Chile for 12 months to learn more about chronic pain and its effects. Researchers looked at how chronic pain relates to mental health issues like depression and anxiety, as well as work stress and daily functioning. The goal wa…
Matched conditions: LONELINESS
Sponsor: Pontificia Universidad Catolica de Chile • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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Loneliness study tests community referrals for seniors
Knowledge-focused CompletedThis study looked at whether referring adults aged 65 and over to local community activities after reablement care can lower their risk of loneliness. Researchers compared in-person activities with online ones in 30 participants. The goal was to see if a full-scale trial is possi…
Matched conditions: LONELINESS
Phase: NA • Sponsor: The University of Northampton • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC
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Can free meals for the whole family boost health and fight loneliness?
Knowledge-focused CompletedThis study looked at whether providing medically tailored meals to an entire household, rather than just one person, and delivering them with a dedicated driver instead of a commercial shipper, can improve diet quality and reduce loneliness. 103 participants were enrolled. The go…
Matched conditions: LONELINESS
Phase: NA • Sponsor: University of North Carolina, Chapel Hill • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC