Loneliness therapy may curb opioid misuse in pain patients

NCT ID NCT06285032

First seen Nov 01, 2025 · Last updated Jun 23, 2026 · Updated 34 times

Summary

This completed study tested whether reducing loneliness through group therapy could lower opioid misuse in 102 adults on long-term opioids for chronic pain. Participants received either cognitive behavior therapy or social navigation in weekly sessions. Researchers measured changes in opioid misuse and pain interference to see if addressing loneliness helps prevent misuse.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • University of Washington

    Seattle, Washington, 98105, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Cognitive Behavior Therapy (CBT) and social navigation

What this could lead to

If it works, this could point toward a way to reduce opioid misuse by addressing loneliness in primary care patients.

What could go wrong

This is a small pilot study with only 102 participants, so results may not apply to everyone. The therapy requires weekly group sessions, which may not suit all patients.

Conditions

The condition(s) this trial relates to.

Chronic Pain chronic pain syndrome opioid abuse

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.