LOCALLY ADVANCED PANCREATIC ADENOCARCINOMA
Clinical trials for LOCALLY ADVANCED PANCREATIC ADENOCARCINOMA explained in plain language.
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New implant tested to shrink tough pancreatic tumors before surgery
Disease control Recruiting nowThis early-stage study is testing a new implant called PTM-101, which is placed near the pancreas to deliver chemotherapy directly to the tumor. The goal is to see if this approach, combined with standard pre-surgery chemo, is safe and can shrink tumors in people with borderline …
Matched conditions: LOCALLY ADVANCED PANCREATIC ADENOCARCINOMA
Phase: PHASE1 • Sponsor: PanTher Therapeutics • Aim: Disease control
Last updated Apr 01, 2026 14:41 UTC
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Electric fields join radiation in fight against pancreatic cancer
Disease control Recruiting nowThis study is testing whether combining precise radiation therapy with a wearable device that creates electric fields around the tumor can slow the growth of locally advanced pancreatic cancer. All 48 participants will receive five days of targeted radiation while wearing the dev…
Matched conditions: LOCALLY ADVANCED PANCREATIC ADENOCARCINOMA
Phase: NA • Sponsor: Baptist Health South Florida • Aim: Disease control
Last updated Apr 01, 2026 14:41 UTC
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New Drug-Radiation combo tested for tough pancreatic tumors
Disease control Recruiting nowThis early-stage study is testing whether a new drug called XER-001, delivered directly to the small intestine, can be safely combined with precise radiation therapy for pancreatic cancer that hasn't spread. Researchers want to find the best dose and see if this combination helps…
Matched conditions: LOCALLY ADVANCED PANCREATIC ADENOCARCINOMA
Phase: PHASE1, PHASE2 • Sponsor: Xerient Pharma • Aim: Disease control
Last updated Apr 01, 2026 14:40 UTC
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New hope in battle against deadly pancreatic cancer
Disease control Recruiting nowThis study is testing which of two chemotherapy combinations works better for people with advanced pancreatic cancer that hasn't been treated before. Researchers will compare NALIRIFOX (a newer combination) against mGAP (a modified version of three existing drugs) in 52 patients.…
Matched conditions: LOCALLY ADVANCED PANCREATIC ADENOCARCINOMA
Phase: PHASE2 • Sponsor: Medical University of South Carolina • Aim: Disease control
Last updated Mar 31, 2026 12:11 UTC
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Scientists reprogram Patient's own fat cells to fight deadly pancreatic cancer
Disease control Recruiting nowThis early-stage study is testing a new personalized treatment called RR001 for people with locally advanced pancreatic cancer. Doctors take a patient's own fat cells, genetically modify them to attack cancer, and give them back after chemotherapy. The main goals are to see if th…
Matched conditions: LOCALLY ADVANCED PANCREATIC ADENOCARCINOMA
Phase: PHASE1, PHASE2 • Sponsor: EIR Biotherapies s.r.l. • Aim: Disease control
Last updated Mar 31, 2026 12:11 UTC
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New drug combo aims to halt tough pancreatic cancer
Disease control Recruiting nowThis study is testing if adding an experimental pill called M3814 to a short, intense course of radiation therapy is safe and more effective than radiation alone for people with locally advanced pancreatic cancer. The goal is to better control the cancer and stop it from growing …
Matched conditions: LOCALLY ADVANCED PANCREATIC ADENOCARCINOMA
Phase: PHASE1, PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 31, 2026 12:10 UTC
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New hope for tough pancreatic cancers: can adding a targeted drug help patients live longer?
Disease control Recruiting nowThis study is for people with advanced pancreatic cancer that has stopped responding to their first treatment. It is testing if adding a targeted drug called panitumumab to standard second-line chemotherapy helps patients live longer than chemotherapy alone. The trial is specific…
Matched conditions: LOCALLY ADVANCED PANCREATIC ADENOCARCINOMA
Phase: PHASE3 • Sponsor: SWOG Cancer Research Network • Aim: Disease control
Last updated Mar 30, 2026 14:35 UTC
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Sound waves supercharge chemo in fight against tough pancreatic cancer
Disease control Recruiting nowThis study is testing whether a new sound wave therapy can make standard chemotherapy work better for people with locally advanced pancreatic cancer that cannot be removed by surgery. About 25 patients will receive the sound wave treatment along with their chemo to see if it help…
Matched conditions: LOCALLY ADVANCED PANCREATIC ADENOCARCINOMA
Phase: PHASE2 • Sponsor: EXACT Therapeutics AS • Aim: Disease control
Last updated Mar 30, 2026 14:31 UTC
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Light therapy trial aims to boost immune attack on pancreatic cancer
Disease control Recruiting nowThis study is testing a new combination treatment for pancreatic cancer that cannot be removed by surgery or has spread. The approach uses a light-activated drug injected into the tumor to help the patient's own immune system, boosted by an immunotherapy drug (pembrolizumab), bet…
Matched conditions: LOCALLY ADVANCED PANCREATIC ADENOCARCINOMA
Phase: PHASE2 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Mar 27, 2026 12:39 UTC
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Turning the inoperable operable: surgery trial offers hope for advanced pancreatic cancer
Disease control Recruiting nowThis international study aims to see if surgery can help patients with advanced pancreatic cancer that was initially considered inoperable. It will follow 150 patients whose tumors shrank or stabilized after several months of strong chemotherapy. The main goal is to understand if…
Matched conditions: LOCALLY ADVANCED PANCREATIC ADENOCARCINOMA
Sponsor: Azienda Ospedaliera di Padova • Aim: Disease control
Last updated Mar 23, 2026 15:18 UTC
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New drug sequence aims to make inoperable pancreatic tumors removable
Disease control Recruiting nowThis study is testing whether giving two different chemotherapy combinations in sequence can better shrink pancreatic tumors that are difficult or impossible to remove with surgery. The goal is to see if this approach makes more tumors operable and improves survival. The trial wi…
Matched conditions: LOCALLY ADVANCED PANCREATIC ADENOCARCINOMA
Phase: PHASE2 • Sponsor: Wake Forest University Health Sciences • Aim: Disease control
Last updated Mar 23, 2026 15:16 UTC
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New Two-Pronged attack on tough pancreatic cancer
Disease control Recruiting nowThis study is testing if a powerful, two-step treatment can better control a hard-to-treat form of pancreatic cancer. First, patients receive two strong chemotherapy drugs in sequence. If the cancer doesn't grow, they then receive a very precise, high-dose form of radiotherapy gu…
Matched conditions: LOCALLY ADVANCED PANCREATIC ADENOCARCINOMA
Phase: PHASE2 • Sponsor: Institut du Cancer de Montpellier - Val d'Aurelle • Aim: Disease control
Last updated Mar 23, 2026 15:15 UTC
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New drug aims to stop deadly clots in pancreatic cancer patients
Prevention Recruiting nowThis study is testing if a drug called Kinisoquin™ can prevent dangerous blood clots in people with advanced pancreatic cancer who are starting chemotherapy. About 480 patients will receive either the study drug or a placebo for 16 weeks to see which group has fewer clots. The go…
Matched conditions: LOCALLY ADVANCED PANCREATIC ADENOCARCINOMA
Phase: PHASE3 • Sponsor: Quercis Pharma AG • Aim: Prevention
Last updated Mar 17, 2026 13:09 UTC