Electric field therapy plus radiation: new hope for pancreas cancer?

NCT ID NCT05679674

Recruiting now Disease control Sponsor: Baptist Health South Florida Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This clinical trial is testing whether adding a device that delivers low-intensity electric fields (Tumor Treating Fields) to targeted radiation therapy can slow tumor growth in people with locally advanced pancreas cancer. Participants will receive radiation for five days and use the device at home for at least 18 hours daily. The study aims to see if this combination improves how long the cancer stays under control.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Stereotactic Ablative Body Radiation (SABR) and Tumor Treating Fields (TTF) device
What this could lead to: If successful, this combination could slow tumor growth and improve progression-free survival for people with locally advanced pancreas cancer.
What could go wrong: This is a small, early-phase trial with only 48 participants. The treatment requires wearing the TTF device at least 18 hours daily, which may be burdensome, and side effects from radiation or the device are possible.

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Conditions

The condition(s) this trial relates to.

malignant pancreatic neoplasm pancreatic adenocarcinoma pancreatic neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LOCALLY ADVANCED LOCALLY ADVANCED PANCREATIC ADENOCARCINOMA PANCREAS CANCER

Contacts and locations

Locations

Miami Cancer Institute at Baptist Health, Inc.
RECRUITING

Miami, Florida, 33176, United States

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