Baptist Health South Florida

This study is for men with high-risk prostate cancer that hasn't spread. It tests how well a short course of hormone therapy (ADT) shrinks the cancer before surgery. Researchers use a special PET scan (PSMA PET/CT) to measure changes in the cancer. The goal is to see if this appr…

This study tests whether adding the drug azeliragon to targeted radiation therapy can safely shrink brain tumors and keep them under control longer. About 46 adults with cancer that has spread to the brain will receive the combination. The goal is to improve tumor response and de…

This study tests a combination of two drugs, zanubrutinib and pemetrexed, in people whose central nervous system lymphoma has returned or not responded to prior treatment. The goal is to see if this approach can shrink tumors and control the disease. About 15 participants will re…

This study tests the drug cabozantinib in 24 people with meningioma (a type of brain tumor) that has returned or worsened after standard treatments like surgery or radiation. The main goal is to see if the drug can stop the tumor from growing for at least 6 months. Participants m…

This study tests whether adding tumor treating fields (TTF) to targeted radiation therapy can slow tumor growth in people with locally advanced pancreas cancer. Participants receive radiation for five days and wear a device that delivers low-intensity electric fields for at least…

This study tests whether giving radiation therapy early to people with spine tumors that are not yet painful can prevent serious problems like fractures, spinal cord compression, or the need for surgery. About 74 adults with advanced solid tumors and high-risk but minimally sympt…

This study tests whether adding the drug ruxolitinib to standard treatment (radiation and temozolomide) helps people with newly diagnosed glioblastoma live longer. About 190 adults will be randomly assigned to receive either the standard treatment alone or standard treatment plus…

This study tests a mouth rinse called MucoLock to see if it can reduce mouth pain or burning. About 25 adults with severe mouth burning will use the rinse three times a day for 28 days. The goal is to find a simple, well-tolerated treatment for this uncomfortable condition.

This study tests a new way to deliver radiation to spine tumors that have spread from other cancers. Instead of the usual 1 or 2 high-dose sessions, the radiation is spread over 5 treatments to reduce side effects. The goal is to see if this approach is safe, tolerable, and helps…

This study collects samples of glioblastoma (a type of brain tumor) and blood from 120 adults during standard surgery. Researchers will examine tissue from different parts of the same tumor to see how they differ. The goal is to learn more about the tumor's structure and behavior…

This study is testing whether a smartphone app can reliably measure thinking and memory changes in 200 adults with brain tumors. Participants will use the app to complete memory, attention, and problem-solving tests, and report their quality of life. The goal is to see if these d…

This study looks at whether a special PET scan using 18F-Fluciclovine can find leftover brain tumor that standard MRI might miss after surgery. About 20 adults who had brain metastasis removed and are scheduled for radiation will get an optional PET scan before radiation. The goa…

This study looks at whether a special imaging agent called 18F-fluciclovine can help doctors see if radiation therapy is working on large brain tumors that have spread from other cancers. About 20 adults with at least one untreated brain tumor larger than 2 cm will get PET/CT sca…