New radiation boost aims to fight pancreatic cancer

NCT ID NCT06453486

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This phase 2 trial is testing whether high-dose radiation therapy, given after initial chemotherapy, can improve outcomes for people with locally advanced pancreatic cancer. About 43 participants whose tumors responded to chemotherapy will receive targeted radiation. Researchers will track overall survival and quality of life to see if this approach is effective.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

high-dose radiation therapy

What this could lead to

If successful, this approach could offer a more effective way to control locally advanced pancreatic cancer, potentially extending survival and improving quality of life.

What could go wrong

This is a small, early-phase trial with only 43 participants. The treatment may not work better than standard care, and radiation can cause side effects like fatigue or digestive issues.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

pancreatic adenocarcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • McGill University Health Centre

    RECRUITING

    Montreal, Quebec, H4A 3J1, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Princess Margaret Cancer Centre

    RECRUITING

    Toronto, Ontario, M5G 2M9, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••