LIVER CIRRHOSIS

This study looks at whether the drug Bulevirtide can reduce high blood pressure in the liver (portal hypertension) in people with hepatitis B and D who also have liver cirrhosis. High liver pressure can lead to serious problems, and this treatment aims to control it by suppressin…

This study looks at whether giving pantoprazole (a stomach acid reducer) after routine vein treatment can lower the risk of bleeding in people with cirrhosis and enlarged veins in the esophagus or stomach. About 208 adults will be randomly assigned to receive either pantoprazole …

This study is testing whether a drug called ambrisentan can help people with hepatorenal syndrome, a serious kidney complication that occurs in advanced liver cirrhosis and often leads to death. Researchers are comparing ambrisentan against the standard treatment, terlipressin, i…

This study compares a shortened MRI scan to the standard ultrasound for finding liver cancer in 820 adults with liver cirrhosis. Researchers will also check if blood markers can help with diagnosis. The goal is to see if the faster MRI is more accurate and cost-effective for rout…

This study is testing whether a new blood test, called the GAAD score, can improve the detection of liver cancer in people who are at high risk, such as those with cirrhosis or chronic hepatitis. Around 2,100 participants will get an ultrasound and the GAAD blood test every six m…

This study looks at why people with severe liver disease who are in the intensive care unit (ICU) are at risk for a serious fungal lung infection called invasive pulmonary aspergillosis. Researchers will study 450 patients to find out how common this infection is and what factors…

This study looks at why some people with liver cirrhosis develop a blood clot in the main vein of the liver (portal vein thrombosis). Researchers will examine medical records and imaging from 240 adults to identify patterns and risk factors. The goal is to better predict and mana…

This study tests whether sending mailed invitations and assigning patient navigators can increase the number of people who attend regular liver cancer (HCC) ultrasound screenings. The study includes 652 adults with liver cirrhosis or chronic hepatitis B who are at high risk for l…

This study follows 24 adults with liver cirrhosis who recently had a sudden worsening (decompensation) that required hospital care. Researchers will track their health over time, including lab results and major events like death or liver transplant. The goal is to better understa…

This study looks back at medical records of 624 people with liver cirrhosis who had a procedure called TIPS to relieve pressure in the liver. The goal is to create a simple tool that helps doctors predict which patients are at high risk for a brain complication called hepatic enc…