New hope for deadly Liver-Kidney complication

NCT ID NCT06256432

First seen Apr 16, 2026 ยท Last updated Apr 16, 2026

Summary

This study is testing whether a drug called ambrisentan can help people with hepatorenal syndrome, a serious kidney complication that occurs in advanced liver cirrhosis and often leads to death. Researchers are comparing ambrisentan against the standard treatment, terlipressin, in 54 hospitalized patients to see which better improves kidney function and survival. Participants who receive ambrisentan will continue taking it at home for up to 60 days after leaving the hospital.

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Contacts and locations

Locations

  • All India Institute of Medical Sciences

    New Delhi, National Capital Territory of Delhi, 110029, India

  • Asian Institute of Gastroenterology (AIG)

    Hyderabad, Telangana, 500082, India

  • Aster CMI Hospital

    Bangalore, Karnataka, 560092, India

  • Ganesh Shankar Vidyarthi Memorial (GSVM) Medical College

    Kanpur, Uttar Pradesh, 208002, India

  • Medanta Multi Super Specialty Hospital

    Lucknow, Uttar Pradesh, 226030, India

  • Sir HN Reliance Hospital Foundation

    Mumbai, Maharashtra, 400004, India

Conditions

Explore the condition pages connected to this study.