Scientists observe liver disease progression in 24 patients

NCT ID NCT06380335

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study follows 24 adults with liver cirrhosis who recently had a sudden worsening (decompensation) requiring hospital care. Researchers will track their health over time, including lab results and major events like death or liver transplant. The goal is to better understand the natural course of the disease, not to test a new treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this study could provide better understanding of how liver cirrhosis worsens, potentially guiding future treatments or management strategies.

What could go wrong

This is a small observational study with only 24 participants, so findings may not apply to all patients. It does not test any treatment, so no direct benefit to participants.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cirrhosis of liver End Stage Liver Disease hepatic encephalopathy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Bristol Royal Infirmary

    Bristol, BS2 8HW, United Kingdom

  • Hospital General Universitario Gregorio Marañón

    Madrid, 28007, Spain

  • Hospital Universitario Reina Sofía

    Córdoba, 14004, Spain

  • King's College Hospital

    London, SE5 9RS, United Kingdom

  • Leeds Teaching Hospital NHS Trust

    Leeds, LS9 7TF, United Kingdom

  • Nottingham University Hospital

    Nottingham, NG5 1PB, United Kingdom

  • Royal Infirmary Edinburgh

    Edinburgh, EH16 4SA, United Kingdom

  • Royal Liverpool Hospital

    Liverpool, L7 8XP, United Kingdom

  • Southampton General Hospital

    Southampton, SO16 6YD, United Kingdom

  • St George's Hospital

    London, SW17 0QT, United Kingdom

  • St Mary's Hospital

    London, W2 1NY, United Kingdom

  • Sunderland Royal Hospital

    Sunderland, SR4 7TP, United Kingdom