Scientists observe liver disease progression in 24 patients

NCT ID NCT06380335

Ongoing Knowledge-focused Sponsor: Resolution Therapeutics Limited Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study follows 24 adults with liver cirrhosis who recently had a sudden worsening (decompensation) requiring hospital care. Researchers will track their health over time, including lab results and major events like death or liver transplant. The goal is to better understand the natural course of the disease, not to test a new treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this study could provide better understanding of how liver cirrhosis worsens, potentially guiding future treatments or management strategies.
What could go wrong: This is a small observational study with only 24 participants, so findings may not apply to all patients. It does not test any treatment, so no direct benefit to participants.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for LIVER CIRRHOSIS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

cirrhosis of liver End Stage Liver Disease hepatic encephalopathy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LIVER CIRRHOSIS

Contacts and locations

Locations

Bristol Royal Infirmary

Bristol, BS2 8HW, United Kingdom
Hospital General Universitario Gregorio Marañón

Madrid, 28007, Spain
Hospital Universitario Reina Sofía

Córdoba, 14004, Spain
King's College Hospital

London, SE5 9RS, United Kingdom
Leeds Teaching Hospital NHS Trust

Leeds, LS9 7TF, United Kingdom
Nottingham University Hospital

Nottingham, NG5 1PB, United Kingdom
Royal Infirmary Edinburgh

Edinburgh, EH16 4SA, United Kingdom
Royal Liverpool Hospital

Liverpool, L7 8XP, United Kingdom
Southampton General Hospital

Southampton, SO16 6YD, United Kingdom
St George's Hospital

London, SW17 0QT, United Kingdom
St Mary's Hospital

London, W2 1NY, United Kingdom
Sunderland Royal Hospital

Sunderland, SR4 7TP, United Kingdom

More trials for these conditions

Other studies related to the condition(s) this trial covers.