INFLAMMATORY BOWEL DISEASE (IBD)

This study follows 200 adults with Crohn's disease or ulcerative colitis who are prescribed Zymfentra as part of their regular care. Participants answer online surveys about their bowel habits for one year to see if symptoms improve. The goal is to understand how effective this t…

This study tests a new version of a special nutritional drink for children and adults with severe gut problems, such as inflammatory bowel disease, short bowel syndrome, or severe allergies. The drink is designed to provide complete nutrition when the gut cannot handle regular fo…

This study looks at whether switching to a drug called guselkumab (Tremfya) can help people with inflammatory bowel disease (IBD) who did not get enough relief from ustekinumab. About 200 adults across Canada will take guselkumab for one year, and doctors will track their symptom…

This study tests several new investigational drugs in 140 adults with moderate-to-severe Crohn's disease or ulcerative colitis. The goal is to see if these drugs are safe and can improve symptoms and gut healing. Participants must have a confirmed diagnosis and meet disease activ…

This study is testing whether a smartphone app called SMART-IBD can help teenagers (ages 13-17) with inflammatory bowel disease (IBD) take their medications as prescribed and improve their self-management skills. The app includes daily symptom diaries, medication reminders, educa…

This study is testing whether a 12-week personalized aerobic exercise program delivered via telemedicine can help adults with inactive or mildly active inflammatory bowel disease (IBD) better manage their condition. Researchers will enroll 28 participants to see if the program im…

This study looks at whether people with moderate-to-severe inflammatory bowel disease (IBD) need to routinely take dexamethasone (a steroid) before receiving infliximab to prevent allergic reactions. Researchers will compare those who get the pre-medication as usual with those wh…

This study tests whether a short educational video, along with handouts, can help children and teens with inflammatory bowel disease (IBD) eat fewer ultra-processed foods like packaged snacks and sugary drinks. About 120 participants will track their eating online and receive eit…

This study tests whether a 12-week home-based exercise program can improve quality of life for adults with inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis. Participants will use a smartphone app to follow guided physical activities. The goal is …

This study tests whether a smartphone app called MyIBDDiet can help people with inflammatory bowel disease (IBD) learn about and follow an anti-inflammatory diet. Forty adults with IBD who are not currently in a flare will use the app for one month. Researchers will measure how e…

This study tests an experimental drug called DISC-0974 for people with inflammatory bowel disease (IBD) who also have anemia (low red blood cells). About 21 adults with mild IBD and anemia will receive either the drug or a placebo. The main goal is to see if the drug safely raise…

This study is a registry that collects information from thousands of people with Crohn's disease or ulcerative colitis in Argentina. It does not test any new treatment or drug. Instead, it gathers data on patient demographics, disease details, and safety issues like infections to…

This study is gathering stool, blood, and tissue samples from 120 adults—60 with inflammatory bowel disease (IBD) and 60 without—to identify new biomarkers of intestinal dysbiosis (imbalance in gut bacteria). The goal is to develop a blood test that can help diagnose or monitor I…

This observational study looks for microplastics in children with and without inflammatory bowel disease (IBD). Researchers will collect tissue, stool, urine, and blood samples during routine procedures and use a special technique called Raman spectroscopy to detect and count mic…

This early-stage study tests the safety of a new drug called PVT401 in 36 healthy volunteers. The drug is being developed for inflammatory bowel disease (IBD). Participants receive either the drug or a placebo, and researchers monitor side effects and how the drug moves through t…

This study is collecting health information from up to 10,000 people with conditions like Long COVID, ME/CFS, and autoimmune diseases. Participants use a smartphone app to share symptoms, health history, and wearable data. The goal is to better understand these illnesses and help…

This study is tracking 600 adults in South Korea who are already receiving vedolizumab injections for ulcerative colitis or Crohn's disease. Researchers will review medical records to see what side effects occur and how well the treatment works. No new treatments are given—this i…