INFLAMMATORY BOWEL DISEASE (IBD)

This study compares two antibiotics, fidaxomicin and vancomycin, to see which one is better at clearing C. difficile bacteria from the gut in people with inflammatory bowel disease (IBD). About 60 adults with IBD will take one of the two antibiotics for 10 days, and researchers w…

This pilot study will test a new synbiotic formula (SGR11) in 50 adults with mild-to-moderate ulcerative colitis, a type of inflammatory bowel disease. Participants will take the supplement daily for 8 weeks and complete symptom questionnaires, stool tests, and blood tests to see…

This early-stage trial tests whether xylitol, a common sweetener, can safely clear C. difficile bacteria from the gut in people with inflammatory bowel disease (IBD). About 69 adults with mild or inactive IBD will take xylitol by mouth, and researchers will check if the infection…

This study tests whether a special day hospital program helps people with inflammatory bowel disease (IBD) better manage their condition. About 240 adults with Crohn's disease or ulcerative colitis will receive a single visit that combines blood tests, a doctor check, education, …

This study tests whether transferring healthy gut bacteria (via fecal transplant) can improve liver function in people with primary sclerosing cholangitis (PSC) and inflammatory bowel disease (IBD). About 72 adults will receive either a real transplant or a sham procedure, alongs…

This study aims to improve how we screen for colorectal cancer by using a new blood test. Researchers will look for special molecules called oncofetal chondroitin sulfate (ofCS) that appear in tumors. They will collect blood from 2000 people scheduled for a colonoscopy to see if …

This study looks at whether measuring two specific genes (NEAT1 and ANRIL) in a blood sample can help diagnose inflammatory bowel disease (IBD) without needing a colonoscopy. Researchers will enroll 62 newly diagnosed IBD patients and compare their gene levels to their symptoms a…

This study aims to see if data from smartwatches and grocery shopping habits can help detect when inflammatory bowel disease (Crohn's or colitis) is getting worse. About 80 adults on standard IBD treatments will wear a smartwatch and use a loyalty card to track their daily activi…

This study will test a new device called the Magnetic Flexible Endoscope (MFE) in 6 adults with stable inflammatory bowel disease (IBD). The MFE uses a magnet at its tip, moved by an external robotic arm, to travel through the colon. Researchers want to see if it can reach the en…

This study looks at two ways to examine the colon during routine cancer screening in people with inflammatory bowel disease (IBD). One method uses a special dye sprayed inside the colon, while the other uses advanced camera technology to enhance images without dye. About 480 adul…

This study looks at how being overweight or obese might change how well treatments work for people with inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis. Researchers will follow 120 adults with IBD who are on standard therapies, including biologi…