INFLAMMATORY BOWEL DISEASE (IBD)

This pilot study is testing whether a daily synbiotic formula called SGR11 can help improve symptoms and gut health in people with inflammatory bowel disease (IBD). Fifty adults with mild to moderate ulcerative colitis will take the formula for 8 weeks while researchers track the…

This study is testing a new 'one-stop' clinic day for people with Crohn's disease or ulcerative colitis. During a single hospital visit, patients receive blood tests, doctor consultations, education sessions, and other specialized care all together. Researchers want to see if thi…

This small, early-stage study is testing whether a common sweetener called xylitol can safely remove C. difficile bacteria from the gut of people with inflammatory bowel disease (IBD). Researchers will give different doses to small groups of participants to find the highest amoun…

This study is testing whether a fecal microbiota transplant (FMT) can help control primary sclerosing cholangitis (PSC), a rare and serious liver disease often linked with inflammatory bowel disease (IBD). Researchers will compare FMT capsules to placebo capsules in 72 patients w…

This study aims to find out which of two common antibiotics, fidaxomicin or vancomycin, is better at clearing C. difficile bacteria from the gut of people with inflammatory bowel disease (IBD). About 60 adult patients will be randomly assigned to take one of the antibiotics for 1…

This study is testing a new, flexible camera called the Magnetic Flexible Endoscope (MFE) to see if it can safely and comfortably examine the colon in people with stable inflammatory bowel disease (IBD). The device uses a magnet on a robotic arm outside the body to gently guide t…

This study is testing whether a new blood marker can help doctors better identify who needs a colonoscopy for colon cancer screening. Researchers will analyze blood samples from 2,000 people scheduled for colonoscopies to see if this marker, combined with existing stool tests, ca…

This study is comparing two advanced camera techniques used during routine colon cancer screening for people with inflammatory bowel disease (IBD). One method uses a special dye sprayed in the colon, while the newer method uses special camera light filters without any dye. Resear…

This study aims to develop a simple blood test to diagnose inflammatory bowel disease (IBD). Researchers will measure two specific genetic markers in the blood of 62 newly diagnosed patients to see if they can accurately identify IBD. The goal is to find a less invasive alternati…

This is the first study testing a new drug called PVT401 in humans. Researchers want to understand its safety, side effects, and how long it stays in the body. The study involves 36 healthy volunteers who will receive either the drug or a placebo through an IV. The main goal is t…

This study aims to understand if having obesity affects how well standard treatments work for people with Crohn's disease or ulcerative colitis. Researchers will follow 120 adult patients already on treatment to see if their body weight is linked to their treatment response and d…

This study aims to see if data from wearable devices, grocery shopping habits, and patient surveys can be used to predict flare-ups in people with Crohn's disease or ulcerative colitis. Researchers will enroll 80 adults with IBD who are willing to use a smartphone, activity track…