Simple blood test could spare thousands from unneeded colonoscopies

NCT ID NCT07237984

Not yet recruiting Diagnosis Sponsor: Nordsjaellands Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new blood test that looks for special molecules called ofCS, which reappear in most colorectal cancers. Researchers will collect blood and stool samples from 2000 people scheduled for a colonoscopy in Denmark. The goal is to see if combining the blood test with existing stool tests can more accurately identify who truly needs a colonoscopy, reducing unnecessary procedures while still catching cancers early.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Blood test for oncofetal chondroitin sulfate-modified proteoglycans (ofCS)
What this could lead to: If successful, this blood test could help doctors decide who really needs a colonoscopy, catching cancers early while avoiding many unnecessary procedures.
What could go wrong: This is an early-stage study with 2000 people in Denmark. The test may not work as well in larger, more diverse groups, and it is not yet proven to reduce harm or save lives.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for COLORECTAL ADENOMA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

colorectal adenoma colorectal cancer colorectal neoplasm inflammatory bowel disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COLORECTAL ADENOMA COLORECTAL CANCER INFLAMMATORY BOWEL DISEASE (IBD)

Contacts and locations

Locations

Copenhagen University Hospital - Amager-Hvidovre

Hvidovre, 2650, Denmark
Copenhagen University Hospital - North Zealand

Hillerød, 3400, Denmark

More trials for these conditions

Other studies related to the condition(s) this trial covers.