HYPOXIC-ISCHEMIC ENCEPHALOPATHY

This study tests whether the diabetes drug metformin is safe and possible to use in infants who had a brain injury from lack of oxygen at birth (HIE). About 30 babies under 6 months old will receive metformin to see if it helps their brain recovery. The main goal is to check safe…

This study watches people with brain conditions like traumatic brain injury, cerebral palsy, or Alzheimer's who choose to get special nasal treatments with stem cells or exosomes. Researchers do not give the treatment but collect safety data and measure inflammation markers in th…

This study looks at over 3,400 newborns who are not vigorous at birth (between 35 and 42 weeks). Researchers want to see if milking the umbilical cord (pushing blood into the baby) before clamping it leads to fewer cases of brain injury or death compared to clamping the cord righ…

This study is creating a large database of medical information and biological samples from 1,000 infants born with hypoxic-ischemic encephalopathy (HIE), a type of brain injury caused by lack of oxygen. Researchers will measure blood-based biomarkers to better understand the cond…

This study follows 300 children who had seizures as newborns to understand how genes influence their risk of developing epilepsy later in childhood. Researchers will combine genetic, brain scan, and EEG data to create a risk score. The goal is to better predict which children nee…