HYPOXIC ISCHEMIC ENCEPHALOPATHY
Clinical trials for HYPOXIC ISCHEMIC ENCEPHALOPATHY explained in plain language.
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New hope for injured newborn brains: common drug tested in groundbreaking combo therapy
Disease control Not yet recruitingThis study aims to find the right dose of the drug sildenafil (often used for lung pressure) when given alongside standard cooling therapy to newborns with brain injury from oxygen deprivation at birth. It will enroll 24 full-term babies to measure how their bodies process the dr…
Matched conditions: HYPOXIC ISCHEMIC ENCEPHALOPATHY
Phase: PHASE2 • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Disease control
Last updated Mar 19, 2026 14:56 UTC
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Medical gas trial aims to protect newborn brains
Disease control Not yet recruitingThis early study is testing whether adding hydrogen gas to standard cooling therapy is safe and feasible for newborns with moderate-to-severe brain injury caused by oxygen deprivation during birth. The research will involve 54 infants who will receive either standard care alone o…
Matched conditions: HYPOXIC ISCHEMIC ENCEPHALOPATHY
Phase: PHASE1 • Sponsor: Boston Children's Hospital • Aim: Disease control
Last updated Mar 16, 2026 15:24 UTC
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Scientists search for early clues to newborn brain injury
Knowledge-focused Not yet recruitingThis study aims to understand if a protein in the blood, called neurofilament light chain (NfL), can help doctors assess brain injury in newborns who experience oxygen deprivation at birth (hypoxic-ischemic encephalopathy or HIE). Researchers will measure this protein at several …
Matched conditions: HYPOXIC ISCHEMIC ENCEPHALOPATHY
Sponsor: Mustafa Gürkan • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:16 UTC