HYPOXIC-ISCHEMIC ENCEPHALOPATHY
Clinical trials for HYPOXIC-ISCHEMIC ENCEPHALOPATHY explained in plain language.
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Could hydrogen help heal newborn brains? small trial aims to find out
Symptom relief Not yet recruitingThis early-stage study tests whether adding hydrogen gas to standard cooling therapy is safe and doable for newborns who suffered brain injury from oxygen loss at birth. About 54 full-term infants will be randomly assigned to receive either standard cooling alone or cooling plus …
Matched conditions: HYPOXIC-ISCHEMIC ENCEPHALOPATHY
Phase: PHASE1 • Sponsor: Boston Children's Hospital • Aim: Symptom relief
Last updated May 14, 2026 12:04 UTC
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Could a common ED drug help protect newborn brains?
Knowledge-focused Not yet recruitingThis early-phase study looks at how the drug sildenafil (often used for adults) is processed in the bodies of 24 full-term newborns who have suffered brain injury from lack of oxygen at birth. All babies are already receiving standard cooling treatment to protect their brains. Th…
Matched conditions: HYPOXIC-ISCHEMIC ENCEPHALOPATHY
Phase: PHASE2 • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated May 15, 2026 11:57 UTC
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New study tests blood marker for newborn brain injury
Knowledge-focused Not yet recruitingThis study looks at whether a protein called neurofilament light chain (NfL) in the blood can help doctors understand the severity of brain injury in newborns with hypoxic-ischemic encephalopathy (HIE), a condition caused by lack of oxygen at birth. Researchers will measure NfL l…
Matched conditions: HYPOXIC-ISCHEMIC ENCEPHALOPATHY
Sponsor: Mustafa Gürkan • Aim: Knowledge-focused
Last updated May 12, 2026 13:41 UTC