New blood test may predict brain damage in Oxygen-Deprived newborns

NCT ID NCT07292220

Not yet recruiting Knowledge-focused Sponsor: Mustafa Gürkan Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether a protein called neurofilament light chain (NfL) in the blood can help measure brain injury in newborns with hypoxic-ischemic encephalopathy (HIE), a condition caused by lack of oxygen at birth. Researchers will measure NfL levels at several time points in 20 babies undergoing cooling therapy and compare them to healthy newborns. The goal is to see if NfL can serve as a reliable marker for injury severity and recovery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could lead to a simple blood test that helps doctors predict how severe a newborn's brain injury is and guide treatment decisions.
What could go wrong: This is a very small, early study with only 20 participants. It is designed to gather information, not to test a treatment, so it may not lead to any immediate changes in care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

brain hypoxia - ischemia Charcot-Marie-Tooth disease type 1F perinatal asphyxia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HYPOXIC-ISCHEMIC ENCEPHALOPATHY

Contacts and locations

Locations

, Kirikkale University, Department of Pediatrics, Kirikkale

Kirikkale, Yahşihan, 71450, Turkey (Türkiye)

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