HYPOXIC ISCHEMIC ENCEPHALOPATHY

This study tested whether stem cells taken from a patient's own fat and given by IV are safe and might help the brain heal after a traumatic brain injury. 24 adults with long-term brain damage received the treatment. Researchers checked vital signs and measured inflammation marke…

This phase 3 study tested whether high doses of erythropoietin, a hormone that boosts red blood cell production, could improve survival and brain development in full-term newborns who suffered oxygen deprivation at birth. All 120 babies also received standard cooling therapy. The…

This study looked at whether tiny molecules called microRNAs, found in the blood, can help diagnose brain injury in newborns who had a lack of oxygen at birth. Researchers measured microRNA levels in 45 newborns, including healthy babies and those with brain injury. The goal was …

This study tested a sensorimotor program for infants with hypoxic-ischemic encephalopathy (HIE), a brain injury from lack of oxygen at birth. Eleven babies received play-based therapy sessions in the NICU and at home for the first 6 months. The goal was to see if the program was …

This study looked at whether a mother's scent and a soft, knitted octopus toy could reduce pain in newborns who had a lack of oxygen at birth (asphyxia) and were receiving cooling treatment. The study included 45 full-term babies in intensive care. Researchers measured pain level…

This study tested a drug called dexmedetomidine in 50 newborns with brain injury who were undergoing cooling therapy. The goal was to see if it could provide sedation and pain relief as well as morphine, but with fewer risks. Researchers measured safety and drug levels in the blo…

This study looked at whether mothers can safely hold their infants while they undergo therapeutic hypothermia (cooling) for a brain injury called hypoxic-ischemic encephalopathy (HIE). Ten infants were enrolled, and mothers held them for 30 minutes under careful monitoring. The g…

This study looked back at the medical records of 168 adults who survived a cardiac arrest and were treated in the intensive care unit. Researchers wanted to find early signs that could predict which patients were more likely to die within 30 days or six months. By analyzing lab r…

This study looked at 29 children with brain injuries to test two new methods for checking how well the brain controls its own blood flow. The goal was to see if these methods could help doctors better understand and treat brain injuries. The study did not test a treatment, but ai…

This study followed 188 children who had seizures shortly after birth to see how they develop over time. Researchers measured thinking skills, behavior, and daily function. The goal is to understand which children are at higher risk for conditions like cerebral palsy or intellect…