HYPOXIC-ISCHEMIC ENCEPHALOPATHY
Clinical trials for HYPOXIC-ISCHEMIC ENCEPHALOPATHY explained in plain language.
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Could a simple drug shield newborn brains from oxygen loss?
Prevention CompletedThis study tested whether high doses of erythropoietin, a hormone that boosts red blood cell production, could help prevent long-term brain damage in full-term newborns who suffered oxygen deprivation at birth. All 120 babies in the trial also received standard cooling therapy. T…
Matched conditions: HYPOXIC-ISCHEMIC ENCEPHALOPATHY
Phase: PHASE3 • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Prevention
Last updated May 15, 2026 11:53 UTC
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Could a new drug replace morphine for babies undergoing brain cooling?
Symptom relief CompletedThis study tested whether dexmedetomidine, a sedative, is safer than morphine for newborns with brain injury who need cooling therapy. Fifty infants were enrolled to compare side effects and drug levels. The goal is to find a gentler option for pain and sedation that avoids the l…
Matched conditions: HYPOXIC-ISCHEMIC ENCEPHALOPATHY
Phase: PHASE2 • Sponsor: University of Utah • Aim: Symptom relief
Last updated May 17, 2026 22:58 UTC
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Holding hope: new study tests snuggles during baby brain cooling
Symptom relief CompletedThis small study looked at whether it is safe for mothers to hold their infants while they receive cooling therapy for a type of brain injury called hypoxic-ischemic encephalopathy (HIE). Ten babies were enrolled, and researchers checked for problems like the baby getting too war…
Matched conditions: HYPOXIC-ISCHEMIC ENCEPHALOPATHY
Phase: NA • Sponsor: Alexa Craig • Aim: Symptom relief
Last updated May 17, 2026 22:55 UTC
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Knitted octopus and Mom's scent ease pain in sick newborns
Symptom relief CompletedThis study tested whether a mother's scent and a soft, knitted octopus toy could reduce pain in newborns who had birth asphyxia (lack of oxygen) and were receiving cooling treatment. 45 full-term babies in intensive care took part. Researchers measured pain using a special scale.…
Matched conditions: HYPOXIC-ISCHEMIC ENCEPHALOPATHY
Phase: NA • Sponsor: Alev Sivasli • Aim: Symptom relief
Last updated May 17, 2026 22:55 UTC
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Newborn seizure study tracks Kids' brains for years
Knowledge-focused CompletedThis study followed 188 children who had seizures shortly after birth to see how they develop over time. Researchers measured thinking skills, behavior, and daily living abilities to find risk factors for disabilities like cerebral palsy or intellectual disability. The goal is to…
Matched conditions: HYPOXIC-ISCHEMIC ENCEPHALOPATHY
Sponsor: University of California, San Francisco • Aim: Knowledge-focused
Last updated May 17, 2026 23:02 UTC
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New study seeks early clues to survival after cardiac arrest
Knowledge-focused CompletedThis study looked back at the medical records of 168 adults who survived a cardiac arrest and were treated in the ICU. Researchers checked early lab results and other data to find which factors were linked to death within 30 days and up to 6 months. The goal is to help doctors be…
Matched conditions: HYPOXIC-ISCHEMIC ENCEPHALOPATHY
Sponsor: Ahmet Düzgün • Aim: Knowledge-focused
Last updated May 17, 2026 23:02 UTC