New blood test may spot brain damage in newborns faster

NCT ID NCT05986994

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether tiny molecules called microRNAs, found in the blood, can help diagnose brain injury in newborns who had a lack of oxygen at birth. Researchers measured microRNA levels in 45 newborns, including healthy babies and those with brain injury. The goal was to see if these molecules could serve as reliable biomarkers to guide treatment decisions, such as which babies need cooling therapy.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could lead to a simple blood test to help doctors quickly diagnose brain injury in newborns and decide on the best treatment.

What could go wrong

This was a small, completed study with only 45 newborns. More research is needed to confirm if microRNAs are reliable enough for routine use.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Asphyxia brain disorder brain hypoxia - ischemia Hypothermia perinatal asphyxia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Department of Neuroscience, Reproductive and Dentistry Sciences, University of Naples Federico II

    Naples, 80131, Italy

  • Department of Woman and Child, Buon Consiglio Fatebenefratelli Hospital

    Naples, 80123, Italy