New blood test may spot brain damage in newborns faster
NCT ID NCT05986994
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at whether tiny molecules called microRNAs, found in the blood, can help diagnose brain injury in newborns who had a lack of oxygen at birth. Researchers measured microRNA levels in 45 newborns, including healthy babies and those with brain injury. The goal was to see if these molecules could serve as reliable biomarkers to guide treatment decisions, such as which babies need cooling therapy.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this could lead to a simple blood test to help doctors quickly diagnose brain injury in newborns and decide on the best treatment.
- What could go wrong
- This was a small, completed study with only 45 newborns. More research is needed to confirm if microRNAs are reliable enough for routine use.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Department of Neuroscience, Reproductive and Dentistry Sciences, University of Naples Federico II
Naples, 80131, Italy
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Department of Woman and Child, Buon Consiglio Fatebenefratelli Hospital
Naples, 80123, Italy
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