Could a new drug replace morphine for babies undergoing brain cooling?

NCT ID NCT04772222

Completed Symptom relief Sponsor: University of Utah Source: ClinicalTrials.gov ↗

First seen Mar 20, 2026 · Last updated Jun 07, 2026 · Updated 12 times

Summary

This study looked at whether a drug called dexmedetomidine can safely replace morphine for pain and sedation in newborns with brain injury who are being cooled to protect their brains. Fifty full-term babies were enrolled to compare side effects and drug levels. The goal is to find a safer option that avoids the long-term risks linked to opioid use in newborns.

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Contacts and locations

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Locations

Intermountain Medical Center

Murray, Utah, 84107, United States
McKay-Dee Hospital

Ogden, Utah, 84403, United States
Primary Children's Hospital

Salt Lake City, Utah, 84113, United States
University of Utah Health

Salt Lake City, Utah, 84132, United States
Utah Valley Hospital

Provo, Utah, 84604, United States

Conditions

Explore the condition pages connected to this study.

HYPOXIC-ISCHEMIC ENCEPHALOPATHY PAIN