HUMAN IMMUNODEFICIENCY VIRUS

This study looked at how well the HPV vaccine protects against cervical, anal, and oral infections in Rwandan women aged 18-28, both with and without HIV. Researchers measured infection rates and antibody levels years after vaccination. The goal is to confirm long-term protection…

This study looked at 26 adults with HIV whose virus levels stayed high despite taking combination antiretroviral therapy (ART). Researchers wanted to understand why the drugs weren't working and test ways to improve control, such as directly watching patients take their medicatio…

This early-stage trial tested a therapeutic DNA vaccine called ICVAX in 45 adults with HIV who were already on stable antiretroviral therapy (ART). The goal was to see if the vaccine is safe and can strengthen the body's immune response against HIV. Participants received either t…

This early-stage study tested whether giving two lab-made antibodies (3BNC117 and 10-1074) to people with HIV could safely control the virus after they stopped their regular antiretroviral therapy. Twenty-six adults with well-controlled HIV took part. The goal was to see if these…

This study tested whether a combination of two long-acting antibodies (3BNC117-LS and 10-1074-LS) plus an immune-boosting drug (N-803) can safely control HIV in people who temporarily stop their regular antiretroviral therapy. 28 adults with well-controlled HIV took part. The goa…

This study tested whether artesunate vaginal inserts, a medicine used for malaria, can help clear HPV after standard cervical precancer treatment in women living with HIV. 120 women in Kenya used the inserts or a placebo for 5 days on, 1 week off, over 3 cycles. The goal was to s…

This study tested whether bringing together groups of friends who all have HIV can help them support each other to stay in medical care and take their medication. Over 300 people in St. Petersburg, Russia, took part. The approach aimed to improve viral load, clinic visits, and me…

This study tested whether giving extra support to pregnant women with HIV who are at higher risk of dropping out of care can help them stay in treatment and keep the virus under control. The study took place in Kenya and involved 120 women. Researchers used a risk calculator to i…

This study tested whether combining a mobile app with peer support helps Hispanic and Black people living with HIV keep their virus under control. 309 participants were assigned to either the app-plus-peer program or standard care. The goal was to see if more people achieved an u…

This study looked at whether adding an anti-cancer cream (5-fluorouracil) after surgery is an acceptable and useful treatment for cervical precancer in 180 women with HIV in South Africa. The goal was to see if women would stick with the treatment and find it acceptable. The stud…

This study tested a program called THRIVE for 75 hospitalized adults with HIV who were not regularly seeing a doctor. The program provided support to help them attend follow-up appointments after leaving the hospital. The goal was to improve viral load control and reduce anxiety …

This study tested a mobile program to help Romanian gay and bisexual men reduce their risk of HIV and improve mental health. 300 participants used their phones or computers to complete surveys and eight private online sessions with a counselor or by reading health information. Th…

This study tested a tablet-based tool and clinic training to help women learn about HIV prevention options like PrEP. About 141 women from a Florida clinic took part. The goal was to see if the tool helped them decide on and start using prevention methods.

This study tested a program to help young men who have sex with men (ages 17-24) use HIV self-testing and take PrEP, a daily pill that prevents HIV. The program provided information, motivation, and skills through online modules. The goal was to see if it increased HIV testing an…

This study tested a program to help gay and bisexual men in Romania start and stay on PrEP, a daily pill that prevents HIV. 120 men at risk for HIV took part. The program combined in-person visits with a mobile app to support PrEP use. Results will guide similar efforts in other …

This study tested a special counseling program to help people living with HIV quit smoking. The program focused on reducing anxiety and depression, which often make it harder to stop smoking. 131 smokers with HIV took part to see if this approach helped them quit and stay smoke-f…

This study followed 200 transgender and non-binary people living with HIV across Europe for 18 months. Researchers collected data from routine blood tests to see how well HIV treatment was working. The goal was to learn more about this group's health needs and help design better …

This study tested a program where male-female health worker pairs visited pregnant women and their partners at home in Kenya. The goal was to encourage couples to test for HIV together. About 1,600 couples took part, and the study measured how many tested as a couple up to 12 mon…

This study looked at 217 Hispanic people living with HIV to see if the types of bacteria in the anus are linked to HPV infection and anal precancer. Researchers compared samples from California, Mexico, and Puerto Rico. The goal was to understand why anal cancer rates differ amon…

This study tested whether giving recombinant human growth hormone for 48 weeks could reduce the hidden HIV reservoir in people already on successful antiretroviral therapy (ART). 22 adults with undetectable viral loads and healthy immune systems took part. The goal was to see if …

This study looked at how veterans with HIV use the VA's online health portal, My HealtheVet, to manage their condition. Researchers reviewed medical records and interviewed veterans and healthcare providers to understand what helps or hinders use of these tools. The goal was to d…