HUMAN IMMUNODEFICIENCY VIRUS

This study tested a program where HIV nurses were trained to also manage high blood pressure in people living with HIV. The goal was to see if this approach could lower blood pressure over 12 months. The study involved 830 adults at 30 primary health centers in Lagos, Nigeria.

This early study tested a lab-made antibody called 3BNC117-LS in 43 people, some with HIV and some without. The goal was to see if it is safe and how long it stays in the body. If it works, this antibody might one day help control HIV with less frequent dosing.

This study tested whether a vaginal insert containing artesunate, a malaria drug, could help clear HPV after standard cervical precancer treatment in women living with HIV. 120 women in Kenya used the insert or a placebo for 5 nights on and off over 6 weeks. The goal was to see i…

This early-stage trial tested whether a single infusion of two long-acting antibodies plus repeated injections of an immune-stimulating drug can keep HIV under control after people stop their daily antiretroviral therapy. Twenty-eight adults with well-controlled HIV participated.…

This early-stage trial tested a therapeutic DNA vaccine called ICVAX in 45 people with HIV who were already stable on antiretroviral therapy (ART). The goal was to see if the vaccine is safe and whether it can boost the immune system to better control the virus. Participants rece…

This study looked at whether using an anti-cancer cream (5-fluorouracil) in the vagina after surgery is an acceptable and feasible way to treat cervical precancer in 180 South African women living with HIV. The goal was to see if women would stick with the treatment and find it a…

This study tested whether bringing together groups of friends who all have HIV helps them support each other to stay in medical care and take their medications. Over 300 people in St. Petersburg, Russia, took part. The approach uses everyday friendships to encourage regular docto…

This pilot study tested whether screening pregnant women with HIV for their risk of dropping out of care, then offering tailored support (counseling sessions in person or by phone), could help them stay in treatment and keep the virus under control. The study involved 120 women i…

This study tested a program called THRIVE for hospitalized people with HIV who were not regularly seeing a doctor. The program uses acceptance and commitment therapy to help patients overcome avoidance and stigma. Researchers enrolled 75 participants to see if the program was acc…

This early-phase study tested whether two lab-made antibodies (3BNC117 and 10-1074) could help people with HIV control the virus after stopping their daily antiretroviral therapy (ART). Twenty-six participants on stable ART received seven infusions of the antibodies, then paused …

This study tested whether giving recombinant human growth hormone for 48 weeks could reduce the hidden HIV reservoir in people already on successful antiretroviral therapy (ART). The goal was to move toward a 'functional cure' where the body can control the virus without lifelong…

This study tested a program that pairs peer support with a mobile app to help Hispanic and Black people with HIV stay on treatment. 309 participants were randomly assigned to the program or standard care. The goal was to see if the program helps more people achieve an undetectabl…

This study tested whether a couples-focused counseling and testing program could help prevent HIV and improve care. 544 couples from rural South Africa took part. The goal was to see if this approach increases viral suppression and engagement in HIV care.

This study tested a program to help young men (ages 17-24) who have sex with men use HIV self-testing and PrEP (a daily pill to prevent HIV). 118 participants joined the pilot study. The program provided information, motivation, and skills to encourage HIV testing and PrEP use. T…

This study tested a tablet-based tool and clinic training to help women learn about HIV prevention, including PrEP. 141 women from a Florida clinic participated. The goal was to see if these tools helped women make informed choices and start prevention methods.

This study tested a program to help gay and bisexual men in Romania begin and continue taking PrEP, a daily pill that prevents HIV. The program combined in-person counseling, an educational app, and support from doctors. Researchers wanted to see if this approach was practical an…

This study tested whether home visits by male-female pairs of health workers could encourage pregnant women and their male partners to get tested for HIV together. About 1,600 couples in Kenya took part. The goal was to increase couple HIV testing and prevent transmission from mo…

This study tested a mobile program called Comunică to help Romanian gay and bisexual men reduce HIV risk and heavy drinking. 300 participants used their phones or laptops to complete surveys and eight one-hour sessions with a counselor or by reading health information. The progra…

This study tested a 9-session program that uses cognitive-behavioral techniques to help people living with HIV quit smoking by reducing anxiety and depression. 131 daily smokers who were motivated to quit took part. The goal was to see if the program led to more people staying sm…

This study examined how veterans with HIV use My HealtheVet (MHV), an online health portal, to manage their condition. Researchers reviewed medical records and interviewed 123 veterans to understand the impact of MHV on HIV care. The goal was to develop and test an intervention t…

This study followed 200 transgender and non-binary people living with HIV across Europe for 18 months. Researchers collected data from routine blood tests to see how well HIV treatment was working. The goal is to use these findings to create better treatment guidelines and design…

This completed study examined 217 Hispanic people living with HIV in California, Mexico, and Puerto Rico to see if the types of bacteria in the anus are linked to high-risk HPV infection and pre-cancerous lesions. Researchers collected anal swabs and questionnaires to compare mic…

This completed study looked at how well the HPV vaccine protects against HPV infections over time in over 3,000 Rwandan women aged 18-28, some living with HIV and some without. Researchers collected blood, oral, and other samples to measure vaccine effectiveness and long-term ant…

This study looked at 26 adults with HIV whose viral load remained high despite taking combination antiretroviral therapy. Participants stayed in the hospital for a week to take their medications under supervision, while researchers monitored their virus levels and provided counse…