New antibody shot could mean fewer HIV treatments
NCT ID NCT03254277
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This early study tested a lab-made antibody called 3BNC117-LS in 43 people, some with HIV and some without. The goal was to see if it is safe and how long it stays in the body. If it works, this antibody might one day help control HIV with less frequent dosing.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
3BNC117-LS (a lab-made antibody)
What this could lead to
If successful, this could lead to a longer-lasting antibody treatment that helps control HIV without daily pills.
What could go wrong
This is a very early Phase 1 safety study with only 43 participants. The antibody may not work as hoped, and side effects are possible. Much more research is needed.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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The Rockefeller University
New York, New York, 10065, United States