HUMAN IMMUNODEFICIENCY VIRUS

This study tests a program called Khanya, where trained peers (people with lived substance use experience) help HIV patients stick to their medication and reduce drug or alcohol use. The program is offered in steps: a basic version first, then a more intensive one if needed. Rese…

This study tests whether virtual or in-person support helps teens with HIV stay in care and keep the virus under control. About 570 teens aged 15-19 in South Africa will receive either standard care or extra support to prepare for moving to adult clinics. The goal is to see which…

This study tests whether offering lottery-based rewards for saving money can help Kenyan men reduce behaviors that raise their risk for HIV and other STIs. About 1,500 men aged 18-39 who drink alcohol and have paid for sex in the past will be split into two groups. One group gets…

This study compares two ways to provide HIV prevention pills (PrEP) to young people in South Africa: the usual clinic-based approach versus a community-based model where pills are delivered and monitored outside clinics. Researchers will enroll 2,500 participants aged 16-30 to se…

This study tests a program called PRISM that teaches teens with HIV how to manage stress, set goals, and build resilience. It involves three one-on-one sessions with a nurse. The goal is to see if the program is feasible and acceptable, and whether it reduces psychological distre…

This study looks at how HIV infection and aging impact the body's response to the Prevnar 13 vaccine, which protects against pneumococcal bacteria. Researchers will measure antibody levels in the lungs, nasal passages, and blood of participants aged 21-45 or 55-75, comparing thos…

This study aimed to understand how patients and clinic staff feel about using long-acting injectable medications to treat both HIV and opioid use disorder together. Researchers planned to enroll 30 patients and 5-10 staff, giving patients the combined injections and following up …

This study tests whether machine learning can predict which HIV patients are likely to miss clinic visits or have treatment failure. Researchers will give clinic workers risk alerts to help them reach out to high-risk patients. The goal is to improve retention in care and viral s…

This study tests a program called CHIMES designed to help young Black gay and bisexual men living with HIV get better mental health care. The program includes posters, provider training, mental health screening, and case management. Researchers will track whether it leads to more…