Can a simple stress program help teens with HIV in eswatini?

NCT ID NCT07101458

Ongoing Symptom relief Sponsor: Eswatini Nazarene Health Institutions Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jul 01, 2026 · Updated 3 times

Summary

This study tests a program called PRISM that teaches teens with HIV how to manage stress, set goals, and build resilience. It involves three one-on-one sessions with a nurse. The goal is to see if the program is feasible and acceptable, and whether it reduces psychological distress and improves quality of life. The trial includes 140 adolescents aged 10-19 in Eswatini.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Promoting Resilience in Stress Management (PRISM) behavioral intervention
What this could lead to: If it works, this could provide a simple, low-cost way to help teens with HIV manage stress and improve their mental health.
What could go wrong: This is a small pilot study (140 participants) testing feasibility, not effectiveness. The program may not reduce distress or be acceptable to all teens.

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Conditions

The condition(s) this trial relates to.

AIDS HIV infectious disease Stress, Psychological

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HUMAN IMMUNODEFICIENCY VIRUS PSYCHOLOGICAL STRESS

Contacts and locations

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Locations

Raleigh Fitkin Memorial Hospital-Baylor College of Medicine Children's Foundation Clinic

Manzini, Manzini Region, M200, Eswatini

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