Gut bacteria may hold clues to anal cancer risk in hispanic HIV patients

NCT ID NCT06651957

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed study examined 217 Hispanic people living with HIV in California, Mexico, and Puerto Rico to see if the types of bacteria in the anus are linked to high-risk HPV infection and pre-cancerous lesions. Researchers collected anal swabs and questionnaires to compare microbiomes across the three groups. The goal is to understand why anal cancer rates are higher in some populations.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this study could reveal why some Hispanic HIV patients are at higher risk for anal cancer, pointing toward future prevention strategies.

What could go wrong

This is an observational study that only looks for patterns, not a treatment trial. Results may not lead to direct medical changes and may not apply to other populations.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

AIDS anal squamous cell carcinoma anogenital human papillomavirus infection HIV infectious disease human papillomavirus-related squamous cell carcinoma squamous cell intraepithelial neoplasia Squamous Intraepithelial Lesions

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Instituto Nacional de Salud Publica

    Cuernavaca, Morelos, 62100, Mexico

  • University of California, San Francisco

    San Francisco, California, 94143, United States

  • University of Puerto Rico

    San Juan, 00936, Puerto Rico