HELICOBACTER PYLORI INFECTION

This study tested different combinations of the acid-blocker tegoprazan with antibiotics to treat H. pylori, a common stomach infection. 640 adults who had never been treated before received one of several drug regimens for 14 days. The goal was to see which combination worked be…

This study tested different doses of the antibiotics minocycline and metronidazole, combined with bismuth and a stomach acid blocker, to treat Helicobacter pylori infections that didn't clear with previous treatments. 480 adults who had failed earlier therapy were randomly assign…

This study tested two different drug combinations to treat Helicobacter pylori, a stomach infection that can cause ulcers. About 400 adults took either a two-drug regimen (tegoprazan and amoxicillin) or a four-drug regimen (including bismuth and furazolidone). The goal was to see…

This study tested whether a two-drug combination (vonoprazan plus either amoxicillin or doxycycline) works as well as the standard four-drug bismuth quadruple therapy for eradicating H. pylori infection. 579 adults with H. pylori took one of three 14-day treatments. Researchers m…

This study tested a 14-day treatment using two drugs (vonoprazan and amoxicillin) against a more complex seven-then-seven-day regimen for H. pylori infection in 337 adults in Taiwan. The goal was to see if the simpler dual therapy works just as well, with fewer side effects and e…

This study tested whether adding a traditional Chinese herbal formula (Banxiaxiexin decoction) to standard antibiotics can better treat H. pylori infection and related indigestion. 104 adults with both conditions took either the herbal combo or standard therapy for 14 days. The m…

This study tested whether a simpler two-drug treatment (tegoprazan and amoxicillin) works better than the standard four-drug therapy for eradicating H. pylori, a bacteria that can cause stomach ulcers. 370 adults with H. pylori infection were randomly assigned to one of the two t…

This study tested two different 14-day drug combinations to treat Helicobacter pylori, a bacteria that causes stomach inflammation and ulcers. Over 750 adults were randomly assigned to either a triple therapy (omeprazole, amoxicillin, clarithromycin) or a quadruple therapy (omepr…

This study tested whether a new triple therapy containing DWP14012 is as good as the standard treatment for eradicating H. pylori, a bacteria that can cause stomach ulcers. 461 adults with confirmed H. pylori infection took part. The main goal was to see if the infection was gone…

This study tested two different drug combinations in 782 people with H. pylori infection that was resistant to the antibiotic clarithromycin. One group received a triple therapy with a proton pump inhibitor, amoxicillin, and metronidazole, while the other received a quadruple the…

This study tested whether a three-drug combination containing rifabutin can wipe out Helicobacter pylori infections that didn't respond to earlier treatments. 360 adults who had failed prior therapy were randomly assigned to one of three regimens. The goal was to see which approa…

This trial compares two endoscopic techniques—standard white light endoscopy and magnifying endoscopy with narrow-band imaging—to see which better identifies the status of Helicobacter pylori (Hp) infection. About 384 participants will undergo both procedures, and the accuracy of…

This study looked at 42 adults with both H. pylori infection and small intestinal bacterial overgrowth (SIBO). Researchers used advanced DNA and chemical tests on stool samples to map the types of gut bacteria and their byproducts. The goal was to better understand how these two …

This study looked at whether antibiotics for H. pylori (a stomach infection) change the natural bacteria in the vagina. Researchers followed 73 women getting treatment and 10 healthy women. They collected vaginal samples before and after treatment to see if the bacteria mix shift…

This study looked at how a new drug called linaprazan glurate interacts with common antibiotics (clarithromycin, amoxicillin) and bismuth in 56 adults. Some participants were healthy and H. pylori-negative, while others had H. pylori infection. The goal was to measure drug levels…

This study looked back at medical records of 1,730 adults with H. pylori infection who received bismuth-containing quadruple therapy as their first treatment. Researchers compared how well different drug combinations worked and what side effects occurred. The goal was to identify…