HELICOBACTER PYLORI INFECTION
Clinical trials for HELICOBACTER PYLORI INFECTION explained in plain language.
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New study tests better ways to treat stomach bug that causes ulcers
Disease control CompletedThis study looked at how well different bismuth-containing four-drug combinations work to clear H. pylori infection in people who have never been treated before. Researchers reviewed medical records of 1,730 adults aged 18 to 70 to compare success rates and side effects. The goal…
Matched conditions: HELICOBACTER PYLORI INFECTION
Sponsor: Yueyue Li • Aim: Disease control
Last updated Jun 01, 2026 03:24 UTC
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New drug combo shows promise in fighting stomach bug
Disease control CompletedThis study tested two different treatment plans for Helicobacter pylori, a bacteria that can cause stomach ulcers. 400 adults took either a two-drug combination (tegoprazan and amoxicillin) or a four-drug combination (including bismuth and furazolidone). The goal was to see which…
Matched conditions: HELICOBACTER PYLORI INFECTION
Phase: NA • Sponsor: Nanjing First Hospital, Nanjing Medical University • Aim: Disease control
Last updated Jun 01, 2026 03:23 UTC
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Herbal-Drug combo tackles stomach bug and discomfort
Disease control CompletedThis study looked at whether adding a traditional Chinese herbal formula (Banxiaxiexin) to a standard two-drug treatment (vonoprazan and amoxicillin) works better than the drugs alone for people with H. pylori infection and ongoing stomach upset. About 104 adults took part. The g…
Matched conditions: HELICOBACTER PYLORI INFECTION
Phase: PHASE3 • Sponsor: Nanjing First Hospital, Nanjing Medical University • Aim: Disease control
Last updated Jun 01, 2026 03:13 UTC
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New dual drug regimens show promise for stomach bug eradication
Disease control CompletedThis study tested whether a simpler two-drug combination (vonoprazan plus either amoxicillin or doxycycline) works as well as the standard four-drug therapy for eradicating H. pylori, a stomach infection that can cause ulcers. About 579 adults with H. pylori took one of three 14-…
Matched conditions: HELICOBACTER PYLORI INFECTION
Phase: NA • Sponsor: Nanjing First Hospital, Nanjing Medical University • Aim: Disease control
Last updated Jun 01, 2026 03:13 UTC
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New drug combo shows promise for stubborn stomach bug
Disease control CompletedThis study tested whether a three-drug combination including rifabutin can effectively treat Helicobacter pylori infections that did not clear with earlier treatments. Researchers compared this new approach to two other standard therapies in 360 adults. The goal was to find a saf…
Matched conditions: HELICOBACTER PYLORI INFECTION
Phase: PHASE4 • Sponsor: Shanghai Jiao Tong University School of Medicine • Aim: Disease control
Last updated Jun 01, 2026 03:11 UTC
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New two-drug combo may beat standard four-drug therapy for stomach bug
Disease control CompletedThis study tested whether a two-drug combination (tegoprazan and amoxicillin) works better than the standard four-drug therapy for eradicating H. pylori bacteria, which can cause stomach ulcers. 370 adults with H. pylori infection were randomly assigned to one of the two treatmen…
Matched conditions: HELICOBACTER PYLORI INFECTION
Phase: PHASE4 • Sponsor: Zhang Xiaofeng,MD • Aim: Disease control
Last updated Jun 01, 2026 03:11 UTC
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New hope for stubborn stomach bug: study compares two antibiotic combos
Disease control CompletedThis study tested two different antibiotic combinations in 782 adults with a hard-to-treat H. pylori infection that is resistant to the common antibiotic clarithromycin. The goal was to see which treatment works better to clear the infection. Participants received either a triple…
Matched conditions: HELICOBACTER PYLORI INFECTION
Phase: NA • Sponsor: Kangdong Sacred Heart Hospital • Aim: Disease control
Last updated May 29, 2026 14:15 UTC
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New Two-Drug combo may beat standard h. pylori treatment with fewer pills
Disease control CompletedThis study tested a simpler 14-day treatment using two drugs (vonoprazan and amoxicillin) against a more complex standard therapy for H. pylori infection in 337 adults in Taiwan. The goal was to see if the simpler regimen works just as well, with fewer side effects and easier use…
Matched conditions: HELICOBACTER PYLORI INFECTION
Phase: PHASE4 • Sponsor: Fu Jen Catholic University Hospital • Aim: Disease control
Last updated May 26, 2026 12:00 UTC
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New drug combo aims to wipe out stomach bug in phase 3 trial
Disease control CompletedThis study tested a new three-drug combination (DWP14012-based triple therapy) against a standard treatment to see if it can safely and effectively eliminate Helicobacter pylori, a bacteria that can cause stomach ulcers. 461 adults with confirmed H. pylori infection took part. Th…
Matched conditions: HELICOBACTER PYLORI INFECTION
Phase: PHASE3 • Sponsor: Daewoong Pharmaceutical Co. LTD. • Aim: Disease control
Last updated May 26, 2026 12:00 UTC
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New drug combo shows promise for stubborn stomach bug, but side effects common
Disease control CompletedThis study tested a 14-day treatment with minocycline and metronidazole for people whose H. pylori infection did not clear with previous treatments. The new combination worked as well as the standard therapy, but over half of participants had side effects. The goal was to find a …
Matched conditions: HELICOBACTER PYLORI INFECTION
Phase: PHASE4 • Sponsor: Shanghai Jiao Tong University School of Medicine • Aim: Disease control
Last updated May 26, 2026 10:35 UTC
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Which therapy wipes out stomach bug best? triple vs quadruple showdown
Disease control CompletedThis study tested two different 14-day treatments for H. pylori, a bacteria that causes stomach inflammation and ulcers. 752 adults in Pakistan were randomly assigned to either a triple therapy or a bismuth-based quadruple therapy. The goal was to see which treatment cleared the …
Matched conditions: HELICOBACTER PYLORI INFECTION
Phase: PHASE4 • Sponsor: Azfar Farogh • Aim: Disease control
Last updated May 18, 2026 12:11 UTC
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Stomach bug treatment may alter vaginal health, study finds
Knowledge-focused CompletedThis study looked at whether antibiotics for H. pylori infection change the natural bacteria in the vagina. Researchers followed 73 women with H. pylori and 10 without, checking their vaginal discharge before and after treatment. The goal was to understand any shifts in vaginal m…
Matched conditions: HELICOBACTER PYLORI INFECTION
Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University • Aim: Knowledge-focused
Last updated Jun 01, 2026 03:12 UTC
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Scientists map gut bugs in stomach infection and overgrowth combo
Knowledge-focused CompletedThis study looked at 42 adults with both H. pylori infection and small intestinal bacterial overgrowth (SIBO). Researchers used advanced DNA and chemical tests to map the gut bacteria and their metabolic byproducts. The goal was to better understand how these two conditions toget…
Matched conditions: HELICOBACTER PYLORI INFECTION
Sponsor: Zhongshan Hospital (Xiamen), Fudan University • Aim: Knowledge-focused
Last updated May 26, 2026 12:13 UTC