New two-drug combo may beat standard four-drug therapy for stomach bug

NCT ID NCT05647278

Completed Disease control Sponsor: Zhang Xiaofeng,MD Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether a simpler two-drug treatment (tegoprazan and amoxicillin) works better than the standard four-drug therapy for eradicating H. pylori, a bacteria that can cause stomach ulcers. 370 adults with H. pylori infection were randomly assigned to one of the two treatments. The main goal was to see which treatment cleared the infection more effectively after four weeks.

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Conditions

The condition(s) this trial relates to.

Helicobacter pylori infectious disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HELICOBACTER PYLORI INFECTION

Contacts and locations

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Locations

Hangzhou first people's Hospital

Hangzhou, Zhejiang, 310000, China

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