Could a routine blood count reveal hidden stomach infection?

NCT ID NCT07805005

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
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By invitation only
Not open to general applications. Only people the study team invites can take part.
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Paused for now. It may or may not start again.
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The trial has finished. Results may not be published yet.
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Stopped early, before it reached the end. That can be for many reasons, including safety.
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Cancelled before anyone took part.

Expanded access (not trials)

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Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
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Not a trial. The treatment could once be requested outside a study, but no longer can.
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The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

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First seen Sep 04, 2026 · Last updated Sep 09, 2026 · Updated 1 time

Summary

This study tests whether two simple blood markers, the neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR), can signal inflammation caused by Helicobacter pylori infection in the stomach. Researchers will compare these ratios in adults with dyspepsia who have confirmed H. pylori-associated gastritis against those without the infection. All participants undergo endoscopy and biopsy for diagnosis, and the study measures how well the blood ratios predict infection. If the markers hold up, they could offer a quicker, less invasive clue for doctors to consider.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
No drug or treatment is given. The study measures two blood-based inflammatory markers, the neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR), from routine complete blood counts.
What this could lead to
If these blood ratios prove reliable, doctors might use a simple blood test to flag H. pylori-related gastritis before an endoscopy, easing diagnosis.
What could go wrong
This is a small, single-center study, and blood cell ratios can shift with many conditions, so the markers may not be specific enough for routine use.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 90 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Sep 2026

An estimate. Start dates often move.

Expected to finish

May 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adult patients with dyspepsia undergoing endoscopy and biopsy for H. pylori testing at Assiut University Hospitals.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * \- Age 18 years or older * Patients with dyspepsia * Patients undergoing endoscopy and biopsy for H. pylori testing * Willingness to provide informed consent Exclusion Criteria: * \- Hematological diseases * Active infection other than H. pylori * Chronic inflammatory or autoimmune diseases * Malignancy * Recent use of steroids or immunosuppressive drugs * Recent acute bleeding

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

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