Could a routine blood count reveal hidden stomach infection?
NCT ID NCT07805005
First seen Sep 04, 2026 · Last updated Sep 09, 2026 · Updated 1 time
Summary
This study tests whether two simple blood markers, the neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR), can signal inflammation caused by Helicobacter pylori infection in the stomach. Researchers will compare these ratios in adults with dyspepsia who have confirmed H. pylori-associated gastritis against those without the infection. All participants undergo endoscopy and biopsy for diagnosis, and the study measures how well the blood ratios predict infection. If the markers hold up, they could offer a quicker, less invasive clue for doctors to consider.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- No drug or treatment is given. The study measures two blood-based inflammatory markers, the neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR), from routine complete blood counts.
- What this could lead to
- If these blood ratios prove reliable, doctors might use a simple blood test to flag H. pylori-related gastritis before an endoscopy, easing diagnosis.
- What could go wrong
- This is a small, single-center study, and blood cell ratios can shift with many conditions, so the markers may not be specific enough for routine use.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
-
About 90 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
-
Sep 2026
An estimate. Start dates often move.
- Expected to finish
-
May 2028
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Adult patients with dyspepsia undergoing endoscopy and biopsy for H. pylori testing at Assiut University Hospitals.
- Ages
-
18 years and older
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * \- Age 18 years or older * Patients with dyspepsia * Patients undergoing endoscopy and biopsy for H. pylori testing * Willingness to provide informed consent Exclusion Criteria: * \- Hematological diseases * Active infection other than H. pylori * Chronic inflammatory or autoimmune diseases * Malignancy * Recent use of steroids or immunosuppressive drugs * Recent acute bleeding
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Dyspepsia are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
-
The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
-
A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- The RELIEF-trial for patients with upper abdominal pain: study protocol for a randomized controlled trial to investigate the effectiveness of a web-based self-management tool compared with usual care for reduction of healthcare utilization and improvement of patient-reported outcomes
- A simple breath test after a heart attack could prevent dangerous bleeding
- Can a Two-Step antibiotic plan beat stomach bacteria?
- Can a muffin help heal stomach ulcers?
- Beyond h. pylori: a hidden stomach bacteria may influence cancer risk
- Can a closer look at the stomach spot hidden infections?