New combo therapy aims to beat tough stomach bug with fewer side effects

NCT ID NCT06561711

First seen Mar 30, 2026 · Last updated May 16, 2026 · Updated 8 times

Summary

This study tested different doses of two antibiotics (minocycline and metronidazole) in a 14-day bismuth-based treatment for people whose H. pylori infection didn't clear with earlier treatments. The goal was to find a version that kills the bacteria just as well but causes fewer side effects than the standard regimen. 480 adults who had failed prior therapy took part across multiple centers.

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Contacts and locations

Locations

  • Peking University Third Hospital

    Beijing, Beijing Municipality, 100191, China

  • Renji Hospital, School of Medicine, Shanghai Jiao Tong University

    Shanghai, Shanghai Municipality, 200127, China

  • Songjiang Hospital, School of Medicine, Shanghai Jiao Tong University

    Shanghai, Shanghai Municipality, China

  • The Second Affiliated Hospital of Zhejiang University school of Medicine

    Hangzhou, Zhejiang, China

Conditions

Explore the condition pages connected to this study.