Shanghai Jiao Tong University School Of Medicine

This study is testing whether adding a newer brain stimulation treatment, called Magnetic Seizure Therapy (MST), to standard antipsychotic medication helps control symptoms of psychosis faster and with fewer side effects than medication alone. Researchers will compare two groups …

This study is testing if giving strong chemotherapy drugs before surgery can better control aggressive prostate cancer in men. The goal is to shrink the tumor and prevent it from becoming a harder-to-treat, resistant form of the disease. About 300 men with high-risk prostate canc…

This early-stage study is testing a new, one-time gene editing treatment called CS-121 in children and teenagers with a rare, severe genetic disorder that causes extremely high blood fats. The goal is to see if the treatment is safe and can lower fat levels by editing a specific …

This study is testing a new treatment strategy for people with stage II-III HER2-positive breast cancer. The goal is to shrink tumors before surgery using a targeted drug combination. If the tumors shrink well, patients continue with the same drugs; if not, they switch to a diffe…

This study is testing a less intense, 'reduced conditioning' bone marrow transplant for people aged 55 and older with myeloid blood cancers like AML, MDS, and CMML. The goal is to see if using lower doses of chemotherapy drugs (melphalan, busulfan, and fludarabine) before the tra…

This study compares two different drug combinations given before surgery for HER2-positive breast cancer. Researchers want to see if a newer drug (pyrotinib) works as well as the current standard drug (pertuzumab) when combined with two other medications. The study will measure h…

This study aims to find out if a lower dose of a key drug (cyclophosphamide) given after a stem cell transplant works as well as the standard dose to prevent graft-versus-host disease (GVHD). It will involve 316 patients receiving transplants from donors who are not a perfect mat…

This study is testing a combination of two drugs, Sac-TMT and KL-A167, as a treatment given before surgery for triple-negative breast cancer. The goal is to see if this combination can effectively shrink or eliminate the tumor and is safe for patients. The trial will enroll about…

This study is testing a new system to make a specialized camera procedure for the small intestine more accurate and consistent. The procedure uses a special microscope camera to see cells in real-time, like an 'optical biopsy,' to help doctors diagnose conditions like Crohn's dis…

This study aims to see if a newer, enhanced white light used during colonoscopy helps doctors find more pre-cancerous growths (adenomas) than the standard white light. It will involve 800 adults aged 45-85 who are scheduled for a routine colonoscopy. Participants will be randomly…

This study is testing whether a traditional Chinese herbal formula called Shenling Baishu Granule can prevent low-risk colon polyps from growing back after they are removed. About 624 people who recently had these polyps removed will be randomly assigned to take the herbal granul…

This study aims to find early signs of severe lupus in children by looking at their heart function. Researchers will use non-invasive heart scans (echocardiograms) on 60 children with lupus to see if changes in heart muscle can predict which kids have a harder-to-treat form of th…

This study aims to gather long-term information from 600 people with various adrenal gland diseases to better understand these conditions. Researchers will track patients' health over time to learn more about how to diagnose, treat, and predict outcomes for these serious disorder…