Could a lower dose of transplant drug be just as effective?

NCT ID NCT06705062

First seen Mar 21, 2026 · Last updated May 08, 2026 · Updated 3 times

Summary

This study compares a reduced dose (35mg/kg) versus the standard dose (50mg/kg) of a drug called cyclophosphamide, given after a stem cell transplant to prevent graft-versus-host disease (GVHD). About 316 people receiving a transplant from a matched unrelated or half-matched donor will participate. The goal is to see if the lower dose works just as well but with fewer side effects.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-••••

Locations

  • Ruijin hsopital

    RECRUITING

    Shanghai, Shanghai Municipality, 200025, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

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