Shanghai Jiao Tong University School Of Medicine

This study is testing whether a new drug called CS0159, when combined with the diabetes drug semaglutide, can help people with fatty liver disease, obesity, and type 2 diabetes. About 30 adults will take the combination or a placebo for 12 weeks. The main goals are to see if it h…

This study tests a new chemotherapy combination called CAOP for elderly patients (65+) with a rare type of lymphoma called peripheral T-cell lymphoma (PTCL). The goal is to see if replacing a standard drug with a less heart-toxic one can still effectively control the cancer while…

This early-phase study tests a new treatment called VGN-Ex05e for children with autism who have severe, treatment-resistant self-injury or aggression. Six participants aged 7 to 18 will receive a one-time injection into a specific brain area. The main goal is to check safety and …

This study tests a new combination of three drugs (aclarubicin, azacitidine, and venetoclax) for people with acute myeloid leukemia (AML), including those newly diagnosed or whose cancer has returned. The goal is to find the safest dose and see if the combo helps control the dise…

This early-phase trial tests a new cell therapy (ES-NK cells) in 5 to 9 people with severe lupus kidney disease that hasn't responded to standard treatments. The goal is to see if the therapy is safe and can help control the disease. Participants will receive one of three dose le…

This study tests a new combination of drugs (aclarubicin plus cyclophosphamide, vincristine, and prednisone, called CAOP) in 37 people aged 60+ with relapsed or refractory cutaneous T-cell lymphoma (CTCL), a rare skin cancer. The goal is to find the safest dose and see if it shri…

This study tests whether a drug called chiglitazar, combined with anti-inflammatory and liver-protecting treatments, can help people with both type 2 diabetes and a serious fatty liver disease called MASH. About 300 adults will receive either the combination or a placebo to see i…

This study aims to create a better way to detect early stomach cancer during endoscopy. Researchers will develop a diagnostic model using narrow band imaging to help doctors, especially those with less experience, identify cancerous lesions more accurately. The study will involve…

This study tests whether adding an experimental drug (VIC-1911) to two standard medicines can prevent graft-versus-host disease (GVHD) in children aged 8–18 who receive a half-matched stem cell transplant for blood cancers. The trial has two parts: first, checking safety and the …

This study tests whether a capsule form of hyoscine butylbromide (a drug that calms stomach and bowel movements) can improve the view during painless gastrointestinal endoscopy. About 74 adults scheduled for upper GI endoscopy will receive either the drug or a placebo before the …

This study tests whether an artificial intelligence (AI) system can help doctors in general hospitals accurately diagnose small colon polyps (≤5 mm) during a colonoscopy. If the AI is reliable, doctors may be able to decide on the spot whether to remove or leave the polyp, withou…

This study looks at fluid from peritoneal dialysis to find early warning signs of peritoneal fibrosis, a scarring condition that can make dialysis less effective. Researchers will analyze genetic and metabolic markers in the fluid from 55 participants, including dialysis patients…

This study looks at whether a magnetically-controlled capsule (a pill-sized camera) can safely and effectively check the stomach after surgery in elderly patients or those with other health problems. About 120 participants who have had stomach cancer surgery will either swallow t…