Shanghai Jiao Tong University School Of Medicine

This study tests a combination of two drugs, camrelizumab and ivarmacitinib, as a first treatment for children aged 6-18 with newly diagnosed classical Hodgkin lymphoma. The goal is to see if this approach can achieve a complete metabolic response (no signs of active cancer) whil…

This early study tests whether adding an experimental drug (CS0159) to a standard diabetes medication (semaglutide) can help people with fatty liver disease, obesity, and type 2 diabetes lose weight and improve their health. About 30 adults will take the combination or a placebo …

This phase 2 trial tests a new chemotherapy combination called CAOP for elderly patients (65+) with untreated peripheral T-cell lymphoma, a rare blood cancer. The standard treatment often causes heart damage, but this regimen replaces the heart-toxic drug with a safer one. The st…

This study tests a combination of four chemotherapy drugs (aclarubicin, cyclophosphamide, vincristine, and prednisone) in people with cutaneous T-cell lymphoma that has come back or not responded to prior treatment. The trial has two phases: first, finding the safest dose of acla…

This study tests a combination of three drugs—aclarubicin, azacitidine, and venetoclax—in people with acute myeloid leukemia (AML) who are either newly diagnosed and unable to tolerate standard chemotherapy, or whose cancer has returned or not responded to treatment. The trial ha…

This early study tests a new treatment called ES-NK cells for people with severe lupus nephritis that hasn't responded to standard care. The therapy uses specially grown immune cells to try to control the disease. About 5 to 9 participants will receive different doses to check sa…

This early-phase trial will test a new treatment called VGN-Ex05e, made from human embryonic stem cells, for children and teens with autism who have severe, treatment-resistant self-injury or aggression. The treatment is injected directly into a brain area linked to behavior. Onl…

This early-phase study tests whether adding an experimental drug (VIC-1911) to standard medications can prevent graft-versus-host disease (GVHD) in children aged 8-18 who receive a stem cell transplant from a half-matched donor. GVHD occurs when donor cells attack the child's bod…

This study will develop and test a diagnostic model to help doctors identify early gastric cancer during endoscopy. Researchers will use a special imaging technique called narrow band imaging (NBI) to examine suspicious lesions in 300 patients aged 40-80. The goal is to improve a…

This study tests whether feeding preterm infants breast milk at the same time of day it was expressed can improve their sleep in the NICU. Researchers will compare this circadian-synchronized feeding approach to routine feeding in 120 preterm infants born between 28 and 36 weeks.…

This study tests whether a capsule form of hyoscine butylbromide (Buscopan) can reduce stomach and intestinal movements during painless gastrointestinal endoscopy, potentially improving the doctor's view and procedure accuracy. The trial will involve 74 adults scheduled for upper…

This study tests whether an artificial intelligence (AI) system can help doctors in general hospitals accurately decide how to manage small colon polyps (5mm or smaller) during a colonoscopy. About 363 adults with at least one small polyp will be randomly assigned to have their p…

This study looks at fluid from peritoneal dialysis to find biological markers that could signal peritoneal fibrosis, a common complication. Researchers will analyze genetic material and metabolites from 55 participants, including dialysis patients and healthy controls. The goal i…

This study will test a magnetically-controlled capsule endoscope—a pill-sized camera—to check the stomach after surgery in 120 elderly patients or those with other health conditions. The goal is to see if this less invasive method is as safe and effective as traditional endoscopy…