Stomach acid drugs may skew h. pylori stool test results

NCT ID NCT07516262

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether taking common acid-reducing drugs (proton pump inhibitors, or PPIs) affects the accuracy of a stool DNA test for H. pylori, a stomach bacteria. Researchers will test 25 adults who need PPIs, first while on the drug and then after stopping it for 4 weeks. The goal is to see if the test works better without the drug, which could help doctors diagnose H. pylori more reliably.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Proton Pump Inhibitor (PPI) discontinuation

What this could lead to

If successful, this study could show that stopping PPIs for 4 weeks improves the accuracy of stool DNA tests for H. pylori, leading to better diagnosis without needing a scope.

What could go wrong

This is a very small study (25 people) and only looks at diagnostic accuracy, not treatment. Results may not apply to everyone, and the washout period may be inconvenient or risky for some patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Helicobacter pylori infectious disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Renji Hospital, School of Medicine, Shanghai Jiao Tong University

    RECRUITING

    Shanghai, Shanghai Municipality, 200127, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••