ENDOCRINE SYSTEM DISEASES

This phase 2 trial tested a daily injection called TransCon PTH in 59 adults with hypoparathyroidism, a condition where the body doesn't make enough parathyroid hormone. Participants were randomly assigned to receive either the drug or a placebo for four weeks, followed by an ope…

This study tested a new medicine called LASN01 in 41 adults with thyroid eye disease, a condition that causes eye bulging and discomfort. The goal was to see if LASN01 could safely reduce eye bulging compared to a placebo. Participants received either LASN01 or a dummy treatment …

This pilot study tested whether combining financial navigation (help with costs) and peer support (connecting with others) can help adults with diabetes better manage their condition. 61 participants were randomly assigned to receive either financial navigation alone or financial…

This Phase 3 trial tested a daily injection of TransCon PTH, a synthetic parathyroid hormone, in 84 adults with hypoparathyroidism. The goal was to see if it could help patients maintain normal blood calcium levels while reducing their need for high-dose calcium and vitamin D sup…

This study tested a daily injection called TransCon PTH in 81 adults with hypoparathyroidism, a condition where the body lacks parathyroid hormone, causing low calcium levels. The goal was to see if the drug could bring calcium levels back to normal and allow patients to stop tak…

This study tested a once-weekly injection called lonapegsomatropin in 220 adults with growth hormone deficiency who had already completed a previous trial. The goal was to see if the drug remains safe and effective over a full year. Participants received the injection for 52 week…

This early study tested a device that uses mild electric pulses to regenerate the lining of the upper small intestine in 20 adults with type 2 diabetes. The goal was to see if the procedure is safe and could help lower blood sugar. Participants were on 2-3 diabetes pills and had …

This study tested a medication called tirzepatide in children and teenagers aged 10 to 17 with type 2 diabetes. Participants were already taking metformin or insulin but still had high blood sugar. The goal was to see if tirzepatide could safely lower blood sugar levels better th…

This completed study looked at how COVID-19 infection changes hormone levels and markers of inflammation in 220 hospitalized patients. Researchers measured things like thyroid hormones, testosterone, cortisol, and vitamin D at several points during and after hospitalization. They…