New drug shows promise for bulging eyes in thyroid disease

NCT ID NCT06226545

First seen Mar 21, 2026 · Last updated Jun 16, 2026 · Updated 15 times

Summary

This study tested a new medicine called LASN01 in 41 adults with thyroid eye disease, a condition that causes eye bulging and discomfort. The goal was to see if LASN01 could safely reduce eye bulging compared to a placebo. Participants received either LASN01 or a dummy treatment by IV, and researchers measured changes in eye position and side effects.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Site 101

    San Diego, California, 92093, United States

  • Site 103

    Miami, Florida, 33136, United States

  • Site 104

    Houston, Texas, 77401, United States

  • Site 105

    Palo Alto, California, 94303, United States

  • Site 106

    Houston, Texas, 77030, United States

  • Site 108

    Livonia, Michigan, 48152, United States

  • Site 109

    Seattle, Washington, 98104, United States

  • Site 110

    Wilmington, North Carolina, 28403, United States

  • Site 111

    Beverly Hills, California, 90210, United States

  • Site 112

    Las Vegas, Nevada, 89144, United States

  • Site 201

    London, EC1V 2PD, United Kingdom

  • Site 204

    Newcastle upon Tyne, NE1 4LP, United Kingdom

  • Site 206

    London, NW1 5QH, United Kingdom

  • Site 301

    Seville, 41009, Spain

  • Site 302

    Córdoba, 14012, Spain

Conditions

The condition(s) this trial relates to.

disease of orbital part of eye adnexa endocrine exophthalmos endocrine system disorder exophthalmos eye disorder Graves Ophthalmopathy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.