END-STAGE KIDNEY DISEASE

This study is testing a new type of dialysis machine called the Moda-flx Hemodialysis System. Researchers want to see if it is safe and works well when used at home by people with end-stage kidney disease, compared to when it's used in a professional clinic. The study will enroll…

This study is testing an investigational drug called CSL300 (clazakizumab) to see if it can lower the risk of heart attacks and death in people with end-stage kidney disease who are on dialysis. The trial will enroll over 2,300 adults who have both kidney failure and either heart…

This study aims to find out which of two common blood pressure medications works better for people receiving dialysis. It will compare metoprolol, which is filtered out during dialysis, to carvedilol, which is not. The goal is to see which drug more effectively prevents heart att…

This study is testing if a personalized dialysis schedule, tailored to a patient's remaining kidney function, works better than the standard one-size-fits-all schedule. It will enroll 350 adults with kidney failure who are new to dialysis, along with 140 of their caregivers, and …

This early-stage study is testing a new approach for people who have already received a kidney transplant from a well-matched family donor. Researchers want to see if giving patients stem cells from the same donor, after a special preparation treatment, can teach their immune sys…

This study is testing whether a new digital system for tracking symptoms helps people on dialysis feel better. About 2,400 patients at up to 36 clinics will either use the new tablet-based symptom tracker or receive their usual care for a year. The goal is to see if regularly rep…

This study is testing whether a small, battery-powered headband that delivers a gentle electrical current can reduce chronic pain in people receiving regular kidney dialysis. The trial will enroll 125 adults with end-stage kidney disease who experience significant pain, aiming to…

This is an early safety study to see how a new drug called Eloralintide moves through the body in people with severe kidney disease. Researchers will compare results from 28 participants—some with healthy kidneys and some with severe kidney impairment. The main goal is to underst…