Can a diabetes drug help dialysis patients keep their kidneys working?
NCT ID NCT05715814
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a daily 25 mg dose of empagliflozin (a diabetes drug) is safe and helps preserve remaining kidney function in 20 adults on peritoneal dialysis. Participants must still produce at least 250 mL of urine daily. The trial measures changes in kidney filtration rate and looks for a possible rebound effect after stopping the drug.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- empagliflozin (25 mg once daily)
- What this could lead to
- If it works, this could help people on peritoneal dialysis keep their remaining kidney function longer, potentially reducing dialysis needs.
- What could go wrong
- This is a small pilot study with only 20 participants, so results may not apply to everyone. Empagliflozin can cause side effects like dehydration or urinary infections.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Toronto General Hospital
RECRUITINGToronto, Ontario, M5G2N2, Canada
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