Could a common diabetes drug stop diabetes after kidney transplant?
NCT ID NCT07682350
First seen Jul 02, 2026 ยท Last updated Jul 02, 2026
Summary
This trial tests whether taking dapagliflozin (Forxiga) for 12 months can prevent post-transplant diabetes in kidney transplant recipients who do not have diabetes. The study includes 184 adults who recently received a kidney transplant and are on standard immunosuppressive therapy. Participants are randomly assigned to receive either dapagliflozin or a placebo, and researchers monitor diabetes development, kidney function, and safety over a year.
What this could mean
Our plain-language read of the trial. This is informational only โ not medical advice or a prediction.
- Active substance
- Dapagliflozin (Forxiga)
- What this could lead to
- If it works, this could offer a way to prevent diabetes after kidney transplant, helping patients avoid a lifelong condition and protecting their new kidney.
- What could go wrong
- This is a Phase 2 trial with 184 participants, so results are preliminary. The drug may not reduce diabetes risk or could cause side effects like urinary infections or kidney issues.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Department of Nephrology and Endocrinology.
Copenhagen, 2100, Denmark
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Department of Nephrology, Odense University Hospital
Odense, 5000, Denmark
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Department of Renal Medicine
Aarhus, 8200, Denmark
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