END-STAGE KIDNEY DISEASE

This early-stage study tests whether a stem cell infusion from the same donor can allow kidney transplant recipients to safely stop taking lifelong anti-rejection medications. Ten adults with a well-functioning kidney from a matched living donor will receive the infusion after a …

This study tests whether a personalized dialysis schedule works better than the usual one-size-fits-all approach for people with end-stage kidney disease. About 350 patients will be randomly assigned to either an individualized or standard dialysis plan. Researchers will track em…

This study compares two common heart medications, metoprolol and carvedilol, in people on hemodialysis. The goal is to see which one better prevents major heart events like heart attacks, strokes, heart failure, and death. About 2,540 participants will be randomly assigned to one…

This study is testing a new dialysis machine called Moda-flx in 50 adults with end-stage kidney disease who are already on stable dialysis. The goal is to see if it is safe and works well both in a clinic and at home when used by trained patients or care partners. The study will …

This study is testing an investigational drug called CSL300 to see if it can lower the risk of heart attacks and death in people with end-stage kidney disease who are on dialysis. The trial will enroll over 2,300 adults who have both kidney failure and either diabetes or known he…

This study tests whether using social virtual reality (VR) during dialysis sessions can help reduce loneliness and other symptoms in people with end-stage kidney disease. Sixty participants will use VR glasses for 30-45 minutes during their dialysis treatments over four weeks. Th…

This study compares two ways of monitoring symptoms in people receiving dialysis for end-stage kidney disease. About 2,400 patients across up to 36 U.S. clinics will either use a tablet-based system that tracks symptoms and alerts their care team, or continue with usual care. The…

This study tests a small, battery-powered headband that delivers a gentle electrical stimulation to the scalp to reduce chronic pain in people with end-stage kidney disease who are on dialysis. About 125 adults will use the device at home and report their pain levels. The goal is…

This study looks at how the drug eloralintide moves through the body in people with severe kidney disease or kidney failure compared to healthy people. About 28 adults will get a single shot under the skin and be monitored for about 14 weeks. The goal is to understand dosing and …