New drug aims to shield dialysis patients from deadly staph infections

NCT ID NCT06749457

Recruiting now Disease control Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Aug 14, 2026 · Updated 3 times

Summary

This study tests a new drug called AZD7760 in healthy volunteers and people with end-stage kidney disease who are on dialysis. The goal is to see if the drug is safe and how the body processes it. If it works, it could help prevent serious staph infections that often occur in dialysis patients.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: AZD7760 (a drug given as a single intravenous infusion)
What this could lead to: If successful, this could lead to a new way to prevent dangerous staph infections in people on dialysis, reducing hospital stays and complications.
What could go wrong: This is an early-phase trial (Phase I/IIa) focused on safety and dosing, so it is not yet known if AZD7760 actually works. The drug may cause side effects or fail to show benefit in larger studies.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

chronic kidney disease end stage renal failure Sepsis staphylococcal infection staphylococcus aureus infection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

STAPHYLOCOCCUS AUREUS

Contacts and locations

Locations

Research Site
RECRUITING

Huntsville, Alabama, 35805, United States
Research Site
WITHDRAWN

Chula Vista, California, 91910, United States
Research Site
RECRUITING

Chula Vista, California, 91910, United States
Research Site
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Glendale, California, 91206, United States
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Granada Hills, California, 91344, United States
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Los Angeles, California, 90027, United States
Research Site
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Northridge, California, 91324, United States
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Northridge, California, 91325, United States
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Oxnard, California, 93036, United States
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Riverside, California, 92503, United States
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San Dimas, California, 91773, United States
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Tarzana, California, 91356, United States
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Valencia, California, 91355, United States
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Victorville, California, 92392, United States
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Englewood, Colorado, 80110, United States
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Bradenton, Florida, 34209, United States
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Coral Springs, Florida, 33071, United States
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Hollywood, Florida, 33024, United States
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Orlando, Florida, 32806, United States
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Tampa, Florida, 33603, United States
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Lawrenceville, Georgia, 30046, United States
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Chicago, Illinois, 60640, United States
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Chicago, Illinois, 60643, United States
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Iowa City, Iowa, 52242, United States
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Lexington, Kentucky, 40503, United States
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Baltimore, Maryland, 21225, United States
Research Site
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Detroit, Michigan, 48202, United States
Research Site
RECRUITING

Pontiac, Michigan, 48341, United States
Research Site
RECRUITING

Tupelo, Mississippi, 38801, United States
Research Site
RECRUITING

Kansas City, Missouri, 64111, United States
Research Site
RECRUITING

Lincoln, Nebraska, 68510, United States
Research Site
NOT_YET_RECRUITING

Las Vegas, Nevada, 89128, United States
Research Site
RECRUITING

Jersey City, New Jersey, 07305, United States
Research Site
RECRUITING

Albuquerque, New Mexico, 87109, United States
Research Site
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Ridgewood, New York, 11385, United States
Research Site
WITHDRAWN

Kinston, North Carolina, 28504, United States
Research Site
RECRUITING

Winston-Salem, North Carolina, 27103, United States
Research Site
RECRUITING

Bethlehem, Pennsylvania, 18017, United States
Research Site
WITHDRAWN

Knoxville, Tennessee, 37923, United States
Research Site
RECRUITING

Beaumont, Texas, 77706, United States
Research Site
RECRUITING

Dallas, Texas, 75246, United States
Research Site
RECRUITING

Houston, Texas, 77074, United States
Research Site
RECRUITING

McAllen, Texas, 78503, United States
Research Site
WITHDRAWN

San Antonio, Texas, 78215, United States

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