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New drug aims to shield dialysis patients from deadly staph infections

NCT ID NCT06749457

Recruiting now Disease control Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new drug called AZD7760 in healthy volunteers and people with end-stage kidney disease who are on dialysis. The goal is to see if the drug is safe and how the body processes it. If it works, it could help prevent serious staph infections that often occur in dialysis patients.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

AZD7760 (a drug given as a single intravenous infusion)

What this could lead to

If successful, this could lead to a new way to prevent dangerous staph infections in people on dialysis, reducing hospital stays and complications.

What could go wrong

This is an early-phase trial (Phase I/IIa) focused on safety and dosing, so it is not yet known if AZD7760 actually works. The drug may cause side effects or fail to show benefit in larger studies.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

chronic kidney disease end stage renal failure Sepsis staphylococcal infection staphylococcus aureus infection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

STAPHYLOCOCCUS AUREUS

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Research Site

    RECRUITING

    Huntsville, Alabama, 35805, United States

  • Research Site

    WITHDRAWN

    Chula Vista, California, 91910, United States

  • Research Site

    RECRUITING

    Chula Vista, California, 91910, United States

  • Research Site

    RECRUITING

    Glendale, California, 91206, United States

  • Research Site

    RECRUITING

    Granada Hills, California, 91344, United States

  • Research Site

    RECRUITING

    Los Angeles, California, 90027, United States

  • Research Site

    RECRUITING

    Northridge, California, 91324, United States

  • Research Site

    RECRUITING

    Northridge, California, 91325, United States

  • Research Site

    RECRUITING

    Oxnard, California, 93036, United States

  • Research Site

    RECRUITING

    Riverside, California, 92503, United States

  • Research Site

    RECRUITING

    San Dimas, California, 91773, United States

  • Research Site

    RECRUITING

    Tarzana, California, 91356, United States

  • Research Site

    RECRUITING

    Valencia, California, 91355, United States

  • Research Site

    RECRUITING

    Victorville, California, 92392, United States

  • Research Site

    RECRUITING

    Englewood, Colorado, 80110, United States

  • Research Site

    RECRUITING

    Bradenton, Florida, 34209, United States

  • Research Site

    RECRUITING

    Coral Springs, Florida, 33071, United States

  • Research Site

    RECRUITING

    Hollywood, Florida, 33024, United States

  • Research Site

    RECRUITING

    Orlando, Florida, 32806, United States

  • Research Site

    RECRUITING

    Tampa, Florida, 33603, United States

  • Research Site

    NOT_YET_RECRUITING

    Lawrenceville, Georgia, 30046, United States

  • Research Site

    RECRUITING

    Chicago, Illinois, 60640, United States

  • Research Site

    RECRUITING

    Chicago, Illinois, 60643, United States

  • Research Site

    RECRUITING

    Iowa City, Iowa, 52242, United States

  • Research Site

    NOT_YET_RECRUITING

    Lexington, Kentucky, 40503, United States

  • Research Site

    RECRUITING

    Baltimore, Maryland, 21225, United States

  • Research Site

    RECRUITING

    Detroit, Michigan, 48202, United States

  • Research Site

    RECRUITING

    Pontiac, Michigan, 48341, United States

  • Research Site

    RECRUITING

    Tupelo, Mississippi, 38801, United States

  • Research Site

    RECRUITING

    Kansas City, Missouri, 64111, United States

  • Research Site

    RECRUITING

    Lincoln, Nebraska, 68510, United States

  • Research Site

    RECRUITING

    Jersey City, New Jersey, 07305, United States

  • Research Site

    RECRUITING

    Albuquerque, New Mexico, 87109, United States

  • Research Site

    RECRUITING

    Ridgewood, New York, 11385, United States

  • Research Site

    WITHDRAWN

    Kinston, North Carolina, 28504, United States

  • Research Site

    RECRUITING

    Winston-Salem, North Carolina, 27103, United States

  • Research Site

    RECRUITING

    Bethlehem, Pennsylvania, 18017, United States

  • Research Site

    WITHDRAWN

    Knoxville, Tennessee, 37923, United States

  • Research Site

    RECRUITING

    Beaumont, Texas, 77706, United States

  • Research Site

    RECRUITING

    Dallas, Texas, 75246, United States

  • Research Site

    RECRUITING

    Houston, Texas, 77074, United States

  • Research Site

    RECRUITING

    McAllen, Texas, 78503, United States

  • Research Site

    WITHDRAWN

    San Antonio, Texas, 78215, United States