DRY EYE DISEASE (DED)

This study tests whether Miebo eye drops, used for one month before and 1.5 months after LASIK surgery, can reduce dry eye symptoms in people who already have dry eye disease. One hundred adults will use the drops four times daily. The goal is to see if eye dryness after surgery …

This study tests whether stingless bee honey (Kelulut honey) can help young people with juvenile open-angle glaucoma. Sixty participants will either take 30 grams of honey daily for three months or receive no honey. Researchers will measure changes in inflammation, eye nerve thic…

This study tests a new eye drop called HUC1-394 in 150 adults with moderate to severe dry eye disease. Participants will use the drops or a placebo for a period to see if the drug reduces eye surface damage and improves symptoms. The goal is to find the best dose and frequency.

This study compares three different over-the-counter lubricating eye drops in people with dry eye disease. Researchers will measure how well each drop is tolerated, how much it improves symptoms like discomfort and blurry vision, and its effect on daily visual function. The trial…

This study tests a new eye drop called DFL24498 in people with dry eye disease. About 417 adults will use the drops four times a day for 12 weeks. Researchers will check if the drops improve eye surface health and reduce dryness symptoms compared to a placebo.

This study tests whether licaminlimab eye drops can reduce eye discomfort in people with dry eye disease who have a specific gene variant. About 160 participants will use the drops three times daily for 29 days. The goal is to see if this targeted approach works better than a pla…

This study tests a disposable silicone device that clips onto eyeglasses to trap moisture around the eyes. Thirty-five adults with mild to moderate dry eye will wear it for two hours. Researchers will measure tear film stability, tear volume, and symptom changes before and after …

This study tests whether a special ingredient called trehalose, found in some artificial tears, can improve the eye's natural barrier function in people with dry eye disease. About 30 adults with moderate-to-severe dry eye will use the drops for one month. Researchers will measur…

This study compares two eye drops—SYSTANE PRO and MIEBO—to see if SYSTANE PRO works as well as MIEBO for treating dry eye disease. About 260 adults with moderate dry eye will use one of the two drops for one month. The main goal is to measure changes in dry eye symptoms using a s…

This study tests a new eye drop (FBV_01) that combines an extra ingredient with hyaluronic acid for people with moderate-to-severe dry eye. About 74 adults will use the drop four times a day for 30 days. Researchers will compare it to hyaluronic acid alone to see if the combo is …

This study tests whether a standard cosmetic treatment for eye wrinkles (Tixel) can also improve symptoms and signs of dry eye disease. 36 adults with mild to moderate wrinkles and dry eyes will receive either real Tixel or a sham treatment. The goal is to see if the treatment is…

This study is testing a new eye drop that combines trehalose, sodium hyaluronate, and NAAGA without preservatives. It will enroll 30 adults with dry eye disease who are either new to treatment or unhappy with their current drops. Over 6 months, researchers will track changes in s…

This study tests a gel placed in the tear ducts before cataract surgery to see if it helps dry eye symptoms. Sixty adults with dry eye will receive the gel and be followed for up to 5 months. The main goal is to measure tear film stability, a key sign of eye moisture.

This study tests a device called Rexon-Eye that uses low-level electrical current to treat dry eye disease. Researchers will also analyze tear proteins to see how they change with treatment. The trial involves 75 adults with dry eye and aims to understand both the device's effect…

This study looks at whether a new cyclosporin eye drop (Vevizye®) can reduce inflammation and dryness in people with moderate to severe dry eye disease who still have symptoms after using artificial tears. About 25 adults with chronic dry eye and visible eye redness will use the …

This study is looking at whether GLP-1 receptor agonists—drugs used for type 2 diabetes and obesity—can also improve dry eye disease. Researchers will measure changes in tear stability and eye surface health in 100 patients who have not taken these drugs before. The goal is to un…

This study will test whether 0.1% cyclosporine A eye drops can change the number and behavior of immune cells on the eye's surface in people with dry eye disease. Researchers will use a special microscope to watch these cells move over 12 weeks and compare the drops to a lubricat…