New eye drop targets dry eye by gene type

NCT ID NCT07548632

Recruiting now Symptom relief Sponsor: Oculis Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 07, 2026 · Updated 2 times

Summary

This study tests whether licaminlimab eye drops can reduce eye discomfort in people with dry eye disease who have a specific gene variant. About 160 participants will use the drops three times daily for 29 days. The goal is to see if this targeted approach works better than a placebo.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: licaminlimab eye drops
What this could lead to: If it works, this could point toward a new treatment option for dry eye disease in people with a specific genetic profile.
What could go wrong: This is an early-to-mid stage trial with only 160 participants, so results may not apply to everyone. The treatment may not be more effective than placebo eye drops.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

dry eye syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DRY EYE DISEASE (DED)

Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

CORE, Inc
RECRUITING

Shelby, North Carolina, 28150, United States
East West Eye Institute
RECRUITING

Aliso Viejo, California, 92656, United States
Erie Retina Research
RECRUITING

Erie, Pennsylvania, 16507, United States
Eye Research Foundation
RECRUITING

Newport Beach, California, 92664, United States
Global Research Management
RECRUITING

Glendale, California, 91204, United States
LoBue Laser and Eye Medical Center
RECRUITING

Murrieta, California, 92562, United States
North Bay Eye Associates, Inc.
RECRUITING

Petaluma, California, 94954, United States
Oculus Research, Inc.
RECRUITING

Garner, North Carolina, 27529, United States
Orange County Ophthalmology
RECRUITING

Garden Grove, California, 92843, United States
Piedmont Eye Center, Inc.
RECRUITING

Lynchburg, Virginia, 24502, United States
Scott & Christie and Associates
RECRUITING

Cranberry Township, Pennsylvania, 16066, United States
Segal Drug Trials, Inc.
RECRUITING

Delray Beach, Florida, 33484, United States
Total Eye Care, PA
RECRUITING

Memphis, Tennessee, 38119, United States
Vision Institute
RECRUITING

Colorado Springs, Colorado, 80907, United States

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